The gastrointestinal tract plays a role in the development and treatment of metabolic
diseases. During a meal, the gut provides crucial information to the brain regarding …

Background The glucagon-like peptide-1 (GLP-1) is a multifaceted hormone with broad
pharmacological potential. Among the numerous metabolic effects of GLP-1 are the glucose …

摘要胰高血糖素样肽‐1 (Glucagon‐like peptide‐1, GLP‐1) 是一种细胞类型特异性的胰高血糖
素原翻译后产物. 它是由胰高血糖素原基因所编码的, 在激素, 神经元以及营养的刺激下主要由肠 …

The efficacy of Roux-en-Y gastric-bypass (RYGB) and other bariatric surgeries in the
management of obesity and type 2 diabetes mellitus and novel developments in …

Background After weight loss, changes in the circulating levels of several peripheral
hormones involved in the homeostatic regulation of body weight occur. Whether these …

Neuronal nicotinic acetylcholine receptors (nAChRs) regulate the rewarding actions of
nicotine contained in tobacco that establish and maintain the smoking habit. nAChRs also …

Glucagon-like peptide 1 (GLP-1) is a 30-amino acid peptide hormone produced in the
intestinal epithelial endocrine L-cells by differential processing of proglucagon, the gene …

Results: During the ketogenic VLED, subjects lost 13% of initial weight and fasting BHB
increased from (mean±sem) 0.07±0.00 to 0.48±0.07 mmol/l (P< 0.001). BHB fell to …

The influence of dietary fiber on energy regulation remains controversial. This review
summarizes published studies on the effects of dietary fiber on hunger, satiety, energy …

Despite substantial fluctuations in daily food intake, animals maintain a remarkably stable
body weight, because overall caloric ingestion and expenditure are exquisitely matched …