Respiratory syncytial virus: infection, detection, and new options for prevention and treatment

C Griffiths, SJ Drews, DJ Marchant - Clinical microbiology reviews, 2017 - Am Soc Microbiol
Respiratory syncytial virus (RSV) infection is a significant cause of hospitalization of children
in North America and one of the leading causes of death of infants less than 1 year of age …

Human rhinoviruses

SE Jacobs, DM Lamson, K St. George… - Clinical microbiology …, 2013 - Am Soc Microbiol
Human rhinoviruses (HRVs), first discovered in the 1950s, are responsible for more than
one-half of cold-like illnesses and cost billions of dollars annually in medical visits and …

COVID-19 myocarditis and severity factors: an adult cohort study

KL Ma, ZH Liu, C Cao, MK Liu, J Liao, JB Zou, LX Kong… - MedRxiv, 2020 - medrxiv.org
Background Notwithstanding the clinical hallmarks of COVID-19 patients were reported,
several critical issues still remain mysterious, ie, prognostic factors for COVID-19 including …

Epidemiology of multiple respiratory viruses in childcare attendees

ET Martin, MP Fairchok, ZJ Stednick… - The Journal of …, 2013 - academic.oup.com
Background. The identification of multiple viruses during respiratory illness is increasing with
advances in rapid molecular testing; however, the epidemiology of respiratory viral …

Challenges and opportunities in developing respiratory syncytial virus therapeutics

EAF Simões, JP DeVincenzo, M Boeckh… - The Journal of …, 2015 - academic.oup.com
Two meetings, one sponsored by the Wellcome Trust in 2012 and the other by the Global
Virology Foundation in 2013, assembled academic, public health and pharmaceutical …

[HTML][HTML] Association of higher MERS-CoV virus load with severe disease and death, Saudi Arabia, 2014

DR Feikin, B Alraddadi, M Qutub… - Emerging infectious …, 2015 - ncbi.nlm.nih.gov
Middle East respiratory syndrome coronavirus (MERS-CoV) causes a spectrum of illness.
We evaluated whether cycle threshold (C t) values (which are inversely related to virus load) …

Attenuation of respiratory syncytial virus–induced and RIG-I–dependent type I IFN responses in human neonates and very young children

N Marr, TI Wang, SHY Kam, YS Hu… - The Journal of …, 2014 - journals.aai.org
Newborn infants, including those born at term without congenital disorders, are at high risk
of severe disease from respiratory syncytial virus (RSV) infection. Indeed, our current local …

New molecular virus detection methods and their clinical value in lower respiratory tract infections in children

T Jartti, M Söderlund-Venermo, K Hedman… - Paediatric respiratory …, 2013 - Elsevier
During the past decade, several new respiratory viruses and their subgroups have been
discovered. All these new viruses, as well as previously known respiratory viruses, can be …

Is higher viral load in the upper respiratory tract associated with severe pneumonia? Findings from the PERCH study

DR Feikin, W Fu, DE Park, Q Shi… - Clinical Infectious …, 2017 - academic.oup.com
Background. The etiologic inference of identifying a pathogen in the upper respiratory tract
(URT) of children with pneumonia is unclear. To determine if viral load could provide …

Comparison of two multiplex methods for detection of respiratory viruses: FilmArray RP and xTAG RVP

KH Rand, H Rampersaud… - Journal of Clinical …, 2011 - Am Soc Microbiol
We compared the FilmArray RP (Idaho Technology, Inc., Salt Lake City, UT) and the xTAG
RVP (Luminex Corporation, Toronto, Canada) multiplex respiratory virus PCR methods for …