SUMMARY Riboflavin [7, 8-dimethyl-10-(1′-d-ribityl) isoalloxazine, vitamin B2] is an
obligatory component of human and animal diets, as it serves as the precursor of flavin …

Riboflavin derivatives are essential cofactors for a myriad of flavoproteins. In bacteria, flavins
importance extends beyond their role as intracellular protein cofactors, as secreted flavins …

Riboflavin, the precursor for the cofactors flavin mononucleotide (FMN) and flavin adenine
dinucleotide, is an essential metabolite in all organisms. While the functions for de novo …

From a common ancestor, Streptococcus pneumoniae and Streptococcus mitis evolved in
parallel into one of the most important pathogens and a mutualistic colonizer of humans …

Fusobacterium necrophorum is a Gram-negative, filamentous anaerobe prevalent in the
mucosal flora of animals and humans. It causes necrotic infections in cattle, resulting in a …

Flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) are essential riboflavin-
derived cofactors involved in a myriad of redox reactions across all forms of life …

Peptide-specific conventional T cells have been major targets for designing most
antimycobacterial vaccines. Immune responses mediated by conventional T cells exhibit a …

To resolve the growing problem of drug resistance in the treatment of bacterial and fungal
pathogens, specific cellular targets and pathways can be used as targets for new …

MAIT cells express an invariant TCR that recognizes non-peptidic microbial antigens
presented by the non-polymorphic MHCI-like molecule, MR1. We briefly describe how the …

Pathogenic and non-pathogenic related microorganisms differ in secondary metabolite
production. Here we show that riboflavin overproduction by a fungal pathogen and its …