The population genetics of pathogenic Escherichia coli

E Denamur, O Clermont, S Bonacorsi… - Nature Reviews …, 2021 - nature.com
Escherichia coli is a commensal of the vertebrate gut that is increasingly involved in various
intestinal and extra-intestinal infections as an opportunistic pathogen. Numerous pathotypes …

Xanthomonas diversity, virulence and plant–pathogen interactions

S Timilsina, N Potnis, EA Newberry… - Nature Reviews …, 2020 - nature.com
Xanthomonas spp. encompass a wide range of plant pathogens that use numerous
virulence factors for pathogenicity and fitness in plant hosts. In this Review, we examine …

[HTML][HTML] Extending and improving metagenomic taxonomic profiling with uncharacterized species using MetaPhlAn 4

A Blanco-Míguez, F Beghini, F Cumbo, LJ McIver… - Nature …, 2023 - nature.com
Metagenomic assembly enables new organism discovery from microbial communities, but it
can only capture few abundant organisms from most metagenomes. Here we present …

[HTML][HTML] A functional selection reveals previously undetected anti-phage defence systems in the E. coli pangenome

CN Vassallo, CR Doering, ML Littlehale… - Nature …, 2022 - nature.com
The ancient, ongoing coevolutionary battle between bacteria and their viruses,
bacteriophages, has given rise to sophisticated immune systems including restriction …

[HTML][HTML] A roadmap for genome-based phage taxonomy

D Turner, AM Kropinski, EM Adriaenssens - Viruses, 2021 - mdpi.com
Bacteriophage (phage) taxonomy has been in flux since its inception over four decades ago.
Genome sequencing has put pressure on the classification system and recent years have …

Pharokka: a fast scalable bacteriophage annotation tool

G Bouras, R Nepal, G Houtak, AJ Psaltis… - …, 2023 - academic.oup.com
In recent years, there has been an increasing interest in bacteriophages, which has led to
growing numbers of bacteriophage genomic sequences becoming available. Consequently …

[HTML][HTML] A unified catalog of 204,938 reference genomes from the human gut microbiome

A Almeida, S Nayfach, M Boland, F Strozzi… - Nature …, 2021 - nature.com
Comprehensive, high-quality reference genomes are required for functional characterization
and taxonomic assignment of the human gut microbiota. We present the Unified Human …

Community-led, integrated, reproducible multi-omics with anvi'o

AM Eren, E Kiefl, A Shaiber, I Veseli, SE Miller… - Nature …, 2021 - nature.com
Big data abound in microbiology, but the workflows designed to enable researchers to
interpret data can constrain the biological questions that can be asked. Five years after …

[HTML][HTML] Improved pea reference genome and pan-genome highlight genomic features and evolutionary characteristics

T Yang, R Liu, Y Luo, S Hu, D Wang, C Wang… - Nature …, 2022 - nature.com
Complete and accurate reference genomes and annotations provide fundamental resources
for functional genomics and crop breeding. Here we report a de novo assembly and …

Enterococci enhance Clostridioides difficile pathogenesis

AB Smith, ML Jenior, O Keenan, JL Hart, J Specker… - Nature, 2022 - nature.com
Enteric pathogens are exposed to a dynamic polymicrobial environment in the
gastrointestinal tract. This microbial community has been shown to be important during …