Despite recent rapid advances in medical knowledge that have improved survival,
conventional medical science's understanding of human health and disease relies heavily …

Dietary restriction (DR) has long been viewed as the most robust nongenetic means to
extend lifespan and healthspan. Many aging-associated mechanisms are nutrient …

Why do women live longer than men? Here, we mine rich lodes of demographic data to
reveal that lower female mortality at particular ages is decisive—and that the important ages …

A central prediction of evolutionary theory is that energy invested into reproduction comes at
the expense of somatic maintenance and repair, accelerating biological aging. Supporting …

Radical lifespan disparities exist in the animal kingdom. While the ocean quahog can
survive for half a millennium, the mayfly survives for less than 48 h. The evolutionary …

Life history theory has become a prominent framework in the evolutionary social sciences,
and the concept of trade-offs, the cornerstone of life history theory in studies on non-human …

Evolutionary theory predicts that reproduction entails costs that detract from somatic
maintenance, accelerating biological aging. Despite support from studies in human and non …

Males and females in many species differ in how they age and how long they live. These
differences have motivated much research, concerning both their evolution and the …

Research on sex biases in longevity in mammals often assumes that male investment in
competition results in a female survival advantage that is constant throughout life. We use 35 …

Worldwide increase in life expectancy has boosted research on aging. Overcoming the
concept of chronological age, higher attention has been addressed to biological age, which …