The human volatilome: volatile organic compounds (VOCs) in exhaled breath, skin emanations, urine, feces and saliva

A Amann, B de Lacy Costello, W Miekisch… - Journal of breath …, 2014 - iopscience.iop.org
Breath analysis is a young field of research with its roots in antiquity. Antoine Lavoisier
discovered carbon dioxide in exhaled breath during the period 1777–1783, Wilhelm (Vilém) …

Hybrid volatolomics and disease detection

YY Broza, P Mochalski, V Ruzsanyi… - Angewandte Chemie …, 2015 - Wiley Online Library
This Review presents a concise, but not exhaustive, didactic overview of some of the main
concepts and approaches related to “volatolomics”—an emerging frontier for fast, risk‐free …

Application and development trends of gas chromatography–ion mobility spectrometry for traditional Chinese medicine, clinical, food and environmental analysis

J Yin, M Wu, R Lin, X Li, H Ding, L Han, W Yang… - Microchemical …, 2021 - Elsevier
Abstract Rapid, non-destructive, accurate, and high-throughput screening of volatile
ingredients plays an important role in the field of analysis. Gas chromatography–ion mobility …

Evolution of clinical and environmental health applications of exhaled breath research: Review of methods and instrumentation for gas-phase, condensate, and …

MAG Wallace, JD Pleil - Analytica Chimica Acta, 2018 - Elsevier
Human breath, along with urine and blood, has long been one of the three major biological
media for assessing human health and environmental exposure. In fact, the detection of …

A benchmarking protocol for breath analysis: the peppermint experiment

B Henderson, DM Ruszkiewicz… - Journal of breath …, 2020 - iopscience.iop.org
Sampling of volatile organic compounds (VOCs) has shown promise for detection of a range
of diseases but results have proved hard to replicate due to a lack of standardization. In this …

Targeted breath analysis: exogenous volatile organic compounds (EVOC) as metabolic pathway-specific probes

E Gaude, MK Nakhleh, S Patassini… - Journal of Breath …, 2019 - iopscience.iop.org
Breath research has almost invariably focussed on the identification of endogenous volatile
organic compounds (VOCs) as disease biomarkers. After five decades, a very limited …

A compendium of volatile organic compounds (VOCs) released by human cell lines

W Filipiak, P Mochalski, A Filipiak… - Current medicinal …, 2016 - ingentaconnect.com
Volatile organic compounds (VOCs) offer unique insights into ongoing biochemical
processes in healthy and diseased humans. Yet, their diagnostic use is hampered by the …

Towards standardization in the analysis of breath gas volatiles

J Herbig, J Beauchamp - Journal of breath research, 2014 - iopscience.iop.org
Despite growing interest and considerable progress in breath research over the last decade,
standardized practices for the sampling and analysis of breath gas volatiles remain elusive …

The peppermint breath test benchmark for PTR-MS and SIFT-MS

B Henderson, G Slingers, M Pedrotti… - Journal of Breath …, 2021 - iopscience.iop.org
A major challenge for breath research is the lack of standardization in sampling and
analysis. To address this, a test that utilizes a standardized intervention and a defined study …

Peppermint protocol: first results for gas chromatography-ion mobility spectrometry

DM Ruszkiewicz, R Myers, B Henderson… - Journal of Breath …, 2022 - iopscience.iop.org
Abstract The Peppermint Initiative seeks to inform the standardisation of breath analysis
methods. Five Peppermint Experiments with gas chromatography-ion mobility spectrometry …