[HTML][HTML] Applications and limitations of dendrimers in biomedicine

AA Chis, C Dobrea, C Morgovan, AM Arseniu, LL Rus… - Molecules, 2020 - mdpi.com
Biomedicine represents one of the main study areas for dendrimers, which have proven to
be valuable both in diagnostics and therapy, due to their capacity for improving solubility …

[HTML][HTML] Controlled drug delivery vehicles for cancer treatment and their performance

S Senapati, AK Mahanta, S Kumar… - Signal transduction and …, 2018 - nature.com
Although conventional chemotherapy has been successful to some extent, the main
drawbacks of chemotherapy are its poor bioavailability, high-dose requirements, adverse …

Membrane-destabilizing ionizable phospholipids for organ-selective mRNA delivery and CRISPR–Cas gene editing

S Liu, Q Cheng, T Wei, X Yu, LT Johnson, L Farbiak… - Nature materials, 2021 - nature.com
Endosomal escape remains a fundamental barrier hindering the advancement of nucleic
acid therapeutics. Taking inspiration from natural phospholipids that comprise biological …

Diverse applications of nanomedicine

B Pelaz, C Alexiou, RA Alvarez-Puebla, F Alves… - ACS …, 2017 - ACS Publications
The design and use of materials in the nanoscale size range for addressing medical and
health-related issues continues to receive increasing interest. Research in nanomedicine …

[HTML][HTML] A review on polymer and lipid-based nanocarriers and its application to nano-pharmaceutical and food-based systems

H Lu, S Zhang, J Wang, Q Chen - Frontiers in nutrition, 2021 - frontiersin.org
Recently, owing to well-controlled release, enhanced distribution and increased
permeability, nanocarriers used for alternative drug and food-delivery strategies have …

[HTML][HTML] Nano-drug delivery systems entrapping natural bioactive compounds for cancer: recent progress and future challenges

VP Chavda, AB Patel, KJ Mistry, SF Suthar… - Frontiers in …, 2022 - frontiersin.org
Cancer is a prominent cause of mortality globally, and it becomes fatal and incurable if it is
delayed in diagnosis. Chemotherapy is a type of treatment that is used to eliminate …

State-of-the-art advances of copper-based nanostructures in the enhancement of chemodynamic therapy

YN Hao, WX Zhang, YR Gao, YN Wei, Y Shu… - Journal of Materials …, 2021 - pubs.rsc.org
Chemodynamic therapy (CDT) is a new emerging strategy for the in situ treatment of tumors.
In the microenvironment of tumor cells, CDT may be achieved through the generation of …

Dendrimeric nanosystem consistently circumvents heterogeneous drug response and resistance in pancreatic cancer

J Liu, C Chen, T Wei, O Gayet, C Loncle, L Borge… - …, 2021 - Wiley Online Library
Pancreatic ductal adenocarcinoma (PDAC) is a deadly cancer with no efficacious treatment.
The application of nanomedicine is expected to bring new hope to PDAC treatment. In this …

[HTML][HTML] A recent review on cancer nanomedicine

PM Giri, A Banerjee, B Layek - Cancers, 2023 - mdpi.com
Simple Summary The advancement of nanotechnology over the last three decades has
given new hope to cancer management. The first FDA-approved nanomedicine (DOXIL) was …

[HTML][HTML] Drug resistance in metastatic breast cancer: tumor targeted nanomedicine to the rescue

V Gote, AR Nookala, PK Bolla, D Pal - International journal of molecular …, 2021 - mdpi.com
Breast cancer, specifically metastatic breast, is a leading cause of morbidity and mortality in
women. This is mainly due to relapse and reoccurrence of tumor. The primary reason for …