Qualitative analysis of controlled release ciprofloxacin/carbopol 934 mucoadhesive suspension

S Sahoo, CK Chakraborti… - Journal of advanced …, 2011 - journals.lww.com
Mucoadhesive polymeric (carbopol 934) suspension of ciprofloxacin was prepared by
ultrasonication and optimized with the aim of developing an oral controlled release gastro …

Solubility measurement and various solubility parameters of glipizide in different neat solvents

MA Kalam, A Alshamsan, M Alkholief, IA Alsarra… - ACS …, 2020 - ACS Publications
Glipizide (GLZ) is an oral hypoglycemic agent, which is a weakly aqueous soluble drug. The
solubility values of GLZ in various neat solvents are scarce in the literature. Hence, the …

Preparation and characterization of baicalin-poly-vinylpyrrolidone coprecipitate

B Li, M Wen, W Li, M He, X Yang, S Li - International journal of …, 2011 - Elsevier
Baicalin-polyvinylpyrrolidone (PVP) coprecipitate was prepared by the solvent method of
solid dispersion technology to improve the dissolution rate of baicalin. The coprecipitate was …

Poly (2-ethyl-2-oxazoline) as an alternative to poly (vinylpyrrolidone) in solid dispersions for solubility and dissolution rate enhancement of drugs

H Fael, C Ràfols, AL Demirel - Journal of pharmaceutical sciences, 2018 - Elsevier
Abstract Poly (2-ethyl-2-oxazoline)(PEOX), a biocompatible polymer considered as
pseudopolypeptide, was introduced as a potential alternative to the commonly used …

[PDF][PDF] Improved dissolution and bioavailability of eprosartan mesylate formulated as solid dispersions using conventional methods

PV Dangre, MD Godbole, PV Ingale… - Indian Journal of …, 2016 - researchgate.net
Background: Eprosartan mesylate (EM) is a poorly aqueous soluble drug belonging to BCS-
class II suffers from low bioavailability (13%). The present study involves an effort for …

Structural analysis of ciprofloxacin-carbopol polymeric composites by X-Ray diffraction and Fourier transform infra-red spectroscopy

S Sahoo, CK Chakraborti, S Naik, SC Mishra… - Tropical Journal of …, 2011 - ajol.info
Methods: The ciprofloxacin and Carbopol were mixed in water in a drug: polymer ratio of 1: 5
(w/w) and homogenized to produce uniform composites. X-ray powder diffraction analysis of …

Solubility, the Main Concern for Poorly Water-soluble Drugs: Techniques and Alternatives

K Singh, PA Singh, A Frank, S Arora… - Letters in Drug …, 2024 - benthamdirect.com
The most crucial variable that affects a drug's bioavailability is its aqueous solubility. One of
the most significant issues facing the pharmaceutical business is improving water solubility …

Solid dispersion of praziquantel enhanced solubility and improve the efficacy of the schistosomiasis treatment

CSF Marques, P Rezende, LN Andrade… - Journal of Drug Delivery …, 2018 - Elsevier
Praziquantel (PZQ) is an anthelmintic of choice in the treatment of schistosomiasis. Solvent
evaporation technique produced three different Solid Dispersions (SD)(drug: polymer, w/w) …

Characterization of solid state forms of glipizide

SK Singh, M Gulati, I Kaur - Powder technology, 2014 - Elsevier
In the present study various crystalline forms of glipizide were prepared in order to enhance
dissolution rate of glipizide and to evaluate the stability of developed forms. Four different …

Fundamentals of diffusion and dissolution: dissolution testing of pharmaceuticals

D Kapoor, R Maheshwari, K Verma, S Sharma… - Drug delivery …, 2020 - Elsevier
Disintegration and dissolution are the in vitro performance test procedures for a drug to be
developed and its formulation to be selected for in vivo studies, specifically for orally …