Pulsed electrical field (PEF) energy is a promising technique for catheter ablation of cardiac
arrhythmias. In this article, the key aspects that need to be considered for safe and effective …

In the last three decades, ablation of atrial fibrillation (AF) has become an evidence-based
safe and efficacious treatment for managing the most common cardiac arrhythmia. In 2007 …

Targeted cellular ablation is being increasingly used in the treatment of arrhythmias and
structural heart disease. Catheter-based ablation for atrial fibrillation (AF) is considered a …

Cardiac ablation with irreversible electroporation (IRE) is quickly being established as a
modality of choice for atrial fibrillation treatment. While it has not yet been optimised, IRE has …

Background: Previous animal studies have shown no significant vascular injury from pulsed
electrical field (PEF) ablation. We sought to assess the effect of PEF on swine coronary …

Background Myocardial tissue can be ablated by the application nanosecond pulsed fields
(nsPEFs). The applied electric fields irreversibly permeabilize cell membranes and thereby …

Electroporation with pulsed electric fields show a potential to be applied as an experimental
focal therapy of tumors. Sub-microsecond regime of electric pulses displays unique …

Background Irreversible electroporation (IRE) is a non-thermal cell ablation approach that
induces selective damage to cell membranes only. The purpose of the current study was to …

In gene electrotransfer and cardiac ablation with irreversible electroporation, treated muscle
cells are typically of elongated shape and their orientation may vary. Orientation of cells in …

The field of bioelectrics lies at the intersection of biomedical engineering, biophysics, pulsed
power technology, and bioscience, guided by the underlying theme of using electric pulses …