Optogenetic tools for subcellular applications in neuroscience

BR Rost, F Schneider-Warme, D Schmitz, P Hegemann - Neuron, 2017 - cell.com
The ability to study cellular physiology using photosensitive, genetically encoded molecules
has profoundly transformed neuroscience. The modern optogenetic toolbox includes …

[HTML][HTML] Precise cell behaviors manipulation through light-responsive nano-regulators: recent advance and perspective

Z Wang, X Lu, B Xing - Theranostics, 2019 - ncbi.nlm.nih.gov
Nanotechnology-assisted spatiotemporal manipulation of biological events holds great
promise in advancing the practice of precision medicine in healthcare systems. The …

Bioorthogonal click chemistry enables site‐specific fluorescence labeling of functional NMDA receptors for super‐resolution imaging

F Neubert, G Beliu, U Terpitz, C Werner… - Angewandte Chemie …, 2018 - Wiley Online Library
Super‐resolution microscopy requires small fluorescent labels. We report the application of
genetic code expansion in combination with bioorthogonal click chemistry to label the NR1 …

Opsin 1 and Opsin 2 of the Corn Smut Fungus Ustilago maydis Are Green Light-Driven Proton Pumps

S Panzer, A Brych, A Batschauer, U Terpitz - Frontiers in microbiology, 2019 - frontiersin.org
In fungi, green light is absorbed by rhodopsins, opsin proteins carrying a retinal molecule as
chromophore. The basidiomycete Ustilago maydis, a fungal pathogen that infects corn …

Modified Rhodopsins From Aureobasidium pullulans Excel With Very High Proton-Transport Rates

S Panzer, C Zhang, T Konte, C Bräuer… - Frontiers in molecular …, 2021 - frontiersin.org
Aureobasidium pullulans is a black fungus that can adapt to various stressful conditions like
hypersaline, acidic, and alkaline environments. The genome of A. pullulans exhibits three …

Beta-site APP Cleavage Enzyme 1 Deficiency Enhances Reactive Astrocyte Amyloid Beta Clearance

J Zhou - 2022 - rave.ohiolink.edu
Abnormal accumulation of amyloid beta (Aβ) peptide in the brain is regarded as the possible
causative agent of Alzheimer's disease (AD). Increased production of Aβ or impaired …

Electrophysiological characterization of microbial rhodopsins

J Weissbecker - 2020 - publikationen.ub.uni-frankfurt.de
In optogenetischen Anwendungen, welche die Manipulation von zellulären Aktivitäten durch
Licht ermöglichen, werden die Eigenschaften von mikrobiellen Rhodopsinen, einer Familie …