The neurobiology of suicide

K Van Heeringen, JJ Mann - The Lancet Psychiatry, 2014 - thelancet.com
The stress–diathesis model posits that suicide is the result of an interaction between state-
dependent (environmental) stressors and a trait-like diathesis or susceptibility to suicidal …

The molecular bases of the suicidal brain

G Turecki - Nature Reviews Neuroscience, 2014 - nature.com
Suicide ranks among the leading causes of death around the world and takes a heavy
emotional and public health toll on most societies. Both distal and proximal factors contribute …

[HTML][HTML] Understanding the complex of suicide in depression: from research to clinics

L Orsolini, R Latini, M Pompili, G Serafini… - Psychiatry …, 2020 - ncbi.nlm.nih.gov
Objective Amongst psychiatric disorders, major depressive disorder (MDD) is the most
prevalent, by affecting approximately 15–17% of the population and showing a high suicide …

GWAS of suicide attempt in psychiatric disorders and association with major depression polygenic risk scores

N Mullins, TB Bigdeli, AD Børglum… - American journal of …, 2019 - Am Psychiatric Assoc
Objective: More than 90% of people who attempt suicide have a psychiatric diagnosis;
however, twin and family studies suggest that the genetic etiology of suicide attempt is …

A genome-wide association study of suicide attempts in the million veterans program identifies evidence of pan-ancestry and ancestry-specific risk loci

NA Kimbrel, AE Ashley-Koch, XJ Qin, JH Lindquist… - Molecular …, 2022 - nature.com
To identify pan-ancestry and ancestry-specific loci associated with attempting suicide among
veterans, we conducted a genome-wide association study (GWAS) of suicide attempts within …

Genetics of suicide attempts in individuals with and without mental disorders: a population-based genome-wide association study

A Erlangsen, V Appadurai, Y Wang, G Turecki… - Molecular …, 2020 - nature.com
Family studies have shown an aggregation of suicidal behavior in families. Yet, molecular
studies are needed to identify loci accounting for genetic heritability. We conducted a …

Neuropathology of suicide: recent findings and future directions

PE Lutz, N Mechawar, G Turecki - Molecular psychiatry, 2017 - nature.com
Suicide is a major public health concern and a leading cause of death in most societies.
Suicidal behaviour is complex and heterogeneous, likely resulting from several causes. It …

Genome-wide association study meta-analysis of suicide death and suicidal behavior

QS Li, AA Shabalin, E DiBlasi, S Gopal… - Molecular …, 2023 - nature.com
Suicide is a worldwide health crisis. We aimed to identify genetic risk variants associated
with suicide death and suicidal behavior. Meta-analysis for suicide death was performed …

Epidemiology, neurobiology and pharmacological interventions related to suicide deaths and suicide attempts in bipolar disorder: Part I of a report of the International …

A Schaffer, ET Isometsä, L Tondo… - Australian & New …, 2015 - journals.sagepub.com
Objectives: Bipolar disorder is associated with elevated risk of suicide attempts and deaths.
Key aims of the International Society for Bipolar Disorders Task Force on Suicide included …

Genetic association studies of suicidal behavior: a review of the past 10 years, progress, limitations, and future directions

B Mirkovic, C Laurent, MA Podlipski, T Frebourg… - Frontiers in …, 2016 - frontiersin.org
Suicidal behaviors (SBs), which range from suicidal ideation to suicide attempts and
completed suicide, represent a fatal dimension of mental ill-health. The involvement of …