Black pepper (Piper nigrum L.) is a very widely used spice, known for its pungent constituent
piperine. However, in addition to its culinary uses, pepper has important medicinal and …

Black pepper (Piper nigrum) is one of the most widely used among spices. It is valued for its
distinct biting quality attributed to the alkaloid, piperine. Black pepper is used not only in …

Carbon dots have demonstrated great potential as luminescent nanoparticles in
bioapplications. Although such nanoparticles appear to exhibit low toxicity compared to …

Dietary constituents (eg, in grapefruit juice; NaCl) and phytochemicals (eg, St. John's wort)
are important agents modifying drug metabolism and transport and thereby contribute to …

Herbs are often administered in combination with therapeutic drugs, raising the potential of
herb-drug interactions. An extensive review of the literature identified reported herb-drug …

Piperine is the main compound present in black pepper, and is the carrier of its specific
pungent taste, which is responsible for centuries of human dietary utilization and worldwide …

In India, Ayurveda has made a major contribution to the drug discovery process with new
means of identifying active compounds. Recent advancement in bioavailability …

P‐glycoprotein (Pgp) is a 170 kDa phosphorylated glycoprotein encoded by human MDR1
gene. It is responsible for the systemic disposition of numerous structurally and …

Curcumin as the active compound of turmeric has antioxidative, antiinflammatory,
antimicrobial and anticancer properties among others. However, its disadvantageous …

In Part 2 of this review, a critical examination of the pertinent scientific literature is
undertaken in order to assess the interaction risk that popular dietary supplements may pose …