The pathobiology of human fungal infections
Human fungal infections are a historically neglected area of disease research, yet they
cause more than 1.5 million deaths every year. Our understanding of the pathophysiology of …
cause more than 1.5 million deaths every year. Our understanding of the pathophysiology of …
Know the enemy and know yourself: addressing cryptic fungal pathogens of humans and beyond
“If you know the enemy and know yourself, you need not fear the result of a hundred battles.
If you know yourself but not the enemy, for every victory gained you will also suffer a defeat …
If you know yourself but not the enemy, for every victory gained you will also suffer a defeat …
Perspectives on the future of host-microbe biology from the Council on Microbial Sciences of the American Society for Microbiology
Host-microbe biology (HMB) stands on the cusp of redefinition, challenging conventional
paradigms to instead embrace a more holistic understanding of the microbial sciences. The …
paradigms to instead embrace a more holistic understanding of the microbial sciences. The …
Metabolic homeostasis in fungal infections from the perspective of pathogens, immune cells, and whole-body systems
H Weerasinghe, H Stölting, AJ Rose… - … and Molecular Biology …, 2024 - journals.asm.org
The ability to overcome metabolic stress is a major determinant of outcomes during
infections. Pathogens face nutrient and oxygen deprivation in host niches and during their …
infections. Pathogens face nutrient and oxygen deprivation in host niches and during their …
Genomic diversity of the pathogenic fungus Aspergillus fumigatus in Japan reveals the complex genomic basis of azole resistance
X He, Y Kusuya, D Hagiwara, T Toyotome… - Communications …, 2024 - nature.com
Aspergillus fumigatus is a pathogenic fungus with a global distribution. The emergence of
azole-resistant A. fumigatus (AR Af) other than the TR-mutants is a problem in Japan …
azole-resistant A. fumigatus (AR Af) other than the TR-mutants is a problem in Japan …
Growth, morphology, and formation of cinnabarin in Pycnoporus cinnabarinus in relation to different irradiation spectra
CW Schinagl, B Siewert, F Hammerle, G Spes… - Photochemical & …, 2023 - Springer
Background The demand for natural pigments in general, and for fungi-derived pigments in
particular, is constantly rising. Wood-decomposing fungi represent a promising source for …
particular, is constantly rising. Wood-decomposing fungi represent a promising source for …
Harnessing inter-kingdom metabolic disparities at the human-fungal interface for novel therapeutic approaches
C Costantini, M Pariano, M Puccetti… - Frontiers in Molecular …, 2024 - frontiersin.org
Humans interact with a multitude of microorganisms in various ecological relationships,
ranging from commensalism to pathogenicity. The same applies to fungi, long recognized for …
ranging from commensalism to pathogenicity. The same applies to fungi, long recognized for …
[HTML][HTML] Applications of genome-scale metabolic models to the study of human diseases: A systematic review
Abstract Background and Objectives: Genome-scale metabolic networks (GEMs) represent a
valuable modeling and computational tool in the broad field of systems biology. Their ability …
valuable modeling and computational tool in the broad field of systems biology. Their ability …
Antifungal Drug Discovery Using Bioinformatics Tools
R Verma, D Disha, LA Khan - Advances in Antifungal Drug Development …, 2024 - Springer
Natural compounds have long served as valuable sources of medicine throughout history,
with many commercially significant drugs originating from these compounds. Besides …
with many commercially significant drugs originating from these compounds. Besides …