Ovarian cancer is the third most common gynecologic malignancy worldwide but accounts
for the highest mortality rate among these cancers. A stepwise approach to assessment …

Highlights•Platinum-based chemotherapy remains the most active treatment for ovarian
cancer.•Platinum should not be withheld after response to last platinum and a treatment-free …

PURPOSE We report the final, protocol-specified analysis of overall survival (OS) in GOG-
0218, a phase III, randomized trial of bevacizumab in women with newly diagnosed ovarian …

In this multicenter, open-label, single-arm, Phase II study with Simon two-stage optimum
design (NCT04361370), we investigate the efficacy and safety of triplet maintenance …

Epithelial ovarian cancer (EOC) is usually diagnosed late at an advanced stage. Though
EOC initially responds to treatment, the recurrence rate is pretty high. The efficacy of different …

Background Ovarian cancer remains the most deadly gynecologic cancer with the majority
of patients relapsing within 3 years of diagnosis. Traditional treatment paradigms linked to …

Background This trial investigated the hypothesis that the treatment with trabectedin/PLD
(TP) to extend the platinum-free interval (TFIp) can improve overall survival (OS) in patients …

Ovarian cancer is a malignant disease that affects thousands of patients every year.
Currently, we use surgical techniques for early-stage cancer and chemotherapy treatment …

Importance Quality of life (QoL) is an important consideration in cancer medicine, especially
because drugs are becoming more costly and may only result in modest gains in overall …

Abstract Background Tumor Treating Fields (TTFields) are an anti-mitotic therapy comprising
continuous delivery of low-intensity alternating electric fields at intermediate frequencies to …