Membrane chromatography is mainly used for the separation and purification of proteins
and biological macromolecules in the downstream processing process, also applications in …

The diversity and application of viral products has continued to explode. These modalities
can be vaccines, cancer therapies, and gene therapies. However, their diversity is also the …

Viral vectors are poised to acquire a prominent position in modern medicine and
biotechnology owing to their role as delivery agents for gene therapies, oncolytic agents …

High titer and purity levels are key requirements for virus-based cancer and gene therapy
biopharmaceuticals. However, the task of removing enough host-cell DNA from therapeutic …

Protein A affinity chromatography, which is the standard method for purifying monoclonal
antibodies (mAbs) is expensive and involves elution at acidic pH, which could degrade the …

The success of adeno-associated virus (AAV)-based therapeutics in gene therapy poses the
need for rapid and efficient processes that can support the growing clinical demand …

Flow uniformity within the device is critically important in membrane chromatography.
Recent studies have shown that the design of the device has a significant impact on flow …

Many membranes with various pore structures have been studied for size-based selective
filtration and separation. However, one exhibiting reverse size selectivity has rarely been …

Viruses are an emerging class of biotherapeutics used to treat a variety of diseases. Ion-
exchange membrane chromatography is commonly used for virus purification, with the …

As cases of multidrug resistant bacterial infections increase, scientists and clinicians around
the world are increasingly turning to bacteriophages as alternatives to antibiotics. Even …