Antihypertensive peptides: Production, bioavailability and incorporation into foods

B Hernández-Ledesma, M del Mar Contreras… - Advances in colloid and …, 2011 - Elsevier
Bioactive food peptides are encrypted within the sequence of food proteins but can be
released during food processing (by enzymatic hydrolysis or fermentation) or during …

Nitric oxide and atherosclerosis: an update

C Napoli, F de Nigris, S Williams-Ignarro, O Pignalosa… - Nitric oxide, 2006 - Elsevier
Nitric oxide (NO) is a molecule that has gained recognition as a crucial modulator of
vascular disease. NO has a number of intracellular effects that lead to vasorelaxation …

Antihypertensive peptides from food proteins: a review

D Martínez-Maqueda, B Miralles, I Recio… - Food & function, 2012 - pubs.rsc.org
High blood pressure is considered as a significant health problem worldwide. In addition to
numerous preventive and therapeutic drug treatments, important advances have been …

Antioxidant and vascular protective effects of curcumin and tetrahydrocurcumin in rats with l-NAME-induced hypertension

S Nakmareong, U Kukongviriyapan… - Naunyn-Schmiedeberg's …, 2011 - Springer
Inhibition of nitric oxide synthesis with N ω-nitro-l-arginine methyl ester (l-NAME) induces
marked hypertension and oxidative stress. Curcumin (CUR) has been shown strong …

[HTML][HTML] Antihypertensive peptides from milk proteins

P Jäkälä, H Vapaatalo - Pharmaceuticals, 2010 - mdpi.com
Dietary proteins possess a wide range of nutritional and functional properties. They are used
as a source of energy and amino acids, which are needed for growth and development …

[HTML][HTML] Sinapic acid prevents hypertension and cardiovascular remodeling in pharmacological model of nitric oxide inhibited rats

T Silambarasan, J Manivannan, M Krishna Priya… - PloS one, 2014 - journals.plos.org
Objectives Hypertensive heart disease is a constellation of abnormalities that includes
cardiac fibrosis in response to elevated blood pressure, systolic and diastolic dysfunction …

[HTML][HTML] Tetrahydrocurcumin alleviates hypertension, aortic stiffening and oxidative stress in rats with nitric oxide deficiency

S Nakmareong, U Kukongviriyapan… - Hypertension …, 2012 - nature.com
Tetrahydrocurcumin (THC), a major metabolite of curcumin, possesses strong antioxidant
and cardioprotective properties. However, the activities of THC in hypertension and its …

[HTML][HTML] Hexahydrocurcumin ameliorates hypertensive and vascular remodeling in L-NAME-induced rats

L Panthiya, J Tocharus, A Onsa-Ard… - … et Biophysica Acta (BBA …, 2022 - Elsevier
Hexahydrocurcumin (HHC), a major metabolite of curcumin, possesses several biological
activities such as antioxidant, anti-inflammation, and cardioprotective properties. This study …

Arbutus unedo prevents cardiovascular and morphological alterations in L-NAME-induced hypertensive rats: Part I: Cardiovascular and renal hemodynamic effects of …

S Afkir, TB Nguelefack, M Aziz, J Zoheir… - Journal of …, 2008 - Elsevier
Hypertension induced by nitric oxide synthase inhibition is associated with functional
abnormalities of the heart and kidney. The aim of the present study was to investigate …

[HTML][HTML] Antihypertensive effect of allicin in dexamethasone-induced hypertensive rats

H Dubey, A Singh, AM Patole, CR Tenpe - Integrative medicine research, 2017 - Elsevier
Background Glucocorticoid is among the most commonly prescribed medicine.
Unfortunately, Excess glucocorticoid level leads hypertension in 80–90% patients. Garlic …