Background Psychological treatments occupy an important place in evidence-based mental
health treatments. Now is an exciting time to fuel treatment research: a pressing demand for …

The reactivation of a stored memory in the brain can make the memory transiently labile.
During the time it takes for the memory to restabilize (reconsolidate) the memory can either …

The incentive salience sensitization (ISS) theory of addiction holds that addictive behavior
stems from the ability of drugs to progressively sensitize the brain circuitry that mediates …

Since the introduction of intravenous drug self-administration methodology over 50 years
ago, experimental investigation of addictive behaviour has delivered an enormous body of …

Since its rediscovery at the beginning of the 21st Century, memory reconsolidation has been
proposed to be a therapeutic target for reducing the impact of emotional memories that can …

The re-ignition of memory reconsolidation research sparked by Karim Nader in the early
2000s led to great excitement that 'reconsolidation-based'interventions might be developed …

Long-term memory is achieved through a consolidation process where structural and
molecular changes integrate information into a stable memory. However, environmental …

When consolidated long-term memories are reactivated they can destabilize, rendering the
memory labile and vulnerable to modification. This period of lability is followed by …

Background The reconsolidation blocker propranolol abolishes alcohol and drug-seeking
behavior in rodents and attenuates conditioned emotional responses to drug-cues in …

Extinction within the reconsolidation window, or 'retrieval-extinction', has received much
research interest as a possible technique for targeting the reconsolidation of maladaptive …