Opportunities, barriers, and recommendations in Down syndrome research
JA Hendrix, A Amon, L Abbeduto… - … science of rare …, 2020 - content.iospress.com
BACKGROUND: Recent advances in medical care have increased life expectancy and
improved the quality of life for people with Down syndrome (DS). These advances are the …
improved the quality of life for people with Down syndrome (DS). These advances are the …
Association of Alzheimer disease with life expectancy in people with Down syndrome
MF Iulita, DG Chavez, MK Christensen… - JAMA network …, 2022 - jamanetwork.com
Importance People with Down syndrome have a high risk of developing Alzheimer disease
dementia. However, penetrance and age at onset are considered variable, and the …
dementia. However, penetrance and age at onset are considered variable, and the …
Cognitive decline and dementia in Down syndrome
R Hithersay, S Hamburg, B Knight… - Current opinion in …, 2017 - journals.lww.com
Clinical trials of treatments, particularly in the presymptomatic phase of Alzheimer's disease,
are important to consider in individuals with Down syndrome given their high dementia …
are important to consider in individuals with Down syndrome given their high dementia …
[HTML][HTML] Informant-based assessment instruments for dementia in people with intellectual disability: A systematic review and standardised evaluation
EL Zeilinger, IZ Novakovic, S Komenda… - Research in …, 2022 - Elsevier
Background Dementia in people with intellectual disability (ID) is frequent but hard to
recognise. Evidence-based recommendations for suitable instruments are lacking. Aims The …
recognise. Evidence-based recommendations for suitable instruments are lacking. Aims The …
[HTML][HTML] The LonDownS adult cognitive assessment to study cognitive abilities and decline in Down syndrome
Background: Down syndrome (DS), the most common genetic cause of intellectual disability,
is associated with an ultra-high risk of developing Alzheimer's disease. However, there is …
is associated with an ultra-high risk of developing Alzheimer's disease. However, there is …
The behavioral and psychological symptoms of dementia in down syndrome (BPSD-DS) scale: comprehensive assessment of psychopathology in down syndrome
AD Dekker, S Sacco, A Carfi… - Journal of …, 2018 - content.iospress.com
People with Down syndrome (DS) are prone to develop Alzheimer's disease (AD).
Behavioral and psychological symptoms of dementia (BPSD) are core features, but have not …
Behavioral and psychological symptoms of dementia (BPSD) are core features, but have not …
A 12‐week exercise programme has a positive effect on everyday executive function in young people with Down syndrome: a pilot non‐randomised controlled trial
N Shields, N Mizzi, K Buhlert‐Smith… - Journal of …, 2022 - Wiley Online Library
Background Exercise has the potential to reduce cognitive decline in people with Down
syndrome by maximising their cognitive function. The aim of the study was to determine the …
syndrome by maximising their cognitive function. The aim of the study was to determine the …
A review of measures used in the screening, assessment and diagnosis of dementia in people with an intellectual disability
K McKenzie, D Metcalfe… - Journal of Applied …, 2018 - Wiley Online Library
Background The increasing number of individuals with an intellectual disability who are at
risk of developing dementia highlights the need to use measures with strong psychometric …
risk of developing dementia highlights the need to use measures with strong psychometric …
Screening of cognitive changes in adults with intellectual disabilities: a systematic review
Background and Aims: Screening and assessment of cognitive changes in adults with
Intellectual Disabilities (ID), mainly Down Syndrome (DS), is crucial to offer appropriate …
Intellectual Disabilities (ID), mainly Down Syndrome (DS), is crucial to offer appropriate …