Tumour-Associated Macrophages (TAMs) are one of the pivotal components of the tumour
microenvironment. Their roles in the cancer immunity are complicated, both pro-tumour and …

Macrophages are versatile immune cells with remarkable plasticity, enabling them to adapt
to diverse tissue microenvironments and perform various functions. Traditionally categorized …

The facilitative GLUT1 and GLUT3 hexose transporters are expressed abundantly in
macrophages, but whether they have distinct functions remains unclear. We confirmed that …

Summary T helper type 2 (Th2) cytokine-activated M2 macrophages contribute to
inflammation resolution and wound healing. This study shows that IL-4-primed …

Purpose Dental pulp stem cell-derived exosomes (DPSC-EXO), which have biological
characteristics similar to those of metrocytes, have been found to be closely associated with …

Neutrophil aggregation and clearance are important factors affecting neuroinflammatory
injury during acute ischemic stroke. Emerging evidence suggests that energy metabolism is …

Joint replacement surgery is the most effective treatment for end-stage arthritis. Aseptic
loosening caused by periprosthetic osteolysis is a common complication after joint …

Obesity is characterized by adipose tissue expansion, extracellular matrix remodelling and
unresolved inflammation that contribute to insulin resistance and fibrosis. Adipose tissue …

Glioblastoma (GBM), known as the most malignant and common primary brain tumor of the
central nervous system, has finite therapeutic options and a poor prognosis. Studies have …

Background Targeting the tumor microenvironment represents an emerging therapeutic
strategy for cancer. Macrophages are an essential part of the tumor microenvironment …