Antimicrobial peptides as therapeutic agents: Opportunities and challenges

M Mahlapuu, C Björn, J Ekblom - Critical reviews in biotechnology, 2020 - Taylor & Francis
The rapid development of microbial resistance to conventional antibiotics has accelerated
efforts to find anti-infectives with a novel mode-of-action, which are less prone to bacterial …

Topical antimicrobial peptide formulations for wound healing: Current developments and future prospects

RK Thapa, DB Diep, HH Tønnesen - Acta biomaterialia, 2020 - Elsevier
Antimicrobial peptides (AMPs) are the natural antibiotics recognized for their potent
antibacterial and wound healing properties. Bare AMPs have limited activity following topical …

Surface modification of lipid-based nanoparticles

Y Xu, T Fourniols, Y Labrak, V Préat, A Beloqui… - ACS …, 2022 - ACS Publications
There is a growing interest in the development of lipid-based nanocarriers for multiple
purposes, including the recent increase of these nanocarriers as vaccine components …

Cubosomes for topical delivery of the antimicrobial peptide LL-37

L Boge, K Hallstensson, L Ringstad… - European journal of …, 2019 - Elsevier
In this study, the use of cubosomes for topical delivery of the antimicrobial peptide (AMP) LL-
37 was investigated. Topical delivery of AMPs is of great interest for treatment of skin …

Advances in structural design of lipid-based nanoparticle carriers for delivery of macromolecular drugs, phytochemicals and anti-tumor agents

A Angelova, VM Garamus, B Angelov, Z Tian… - Advances in colloid and …, 2017 - Elsevier
The present work highlights recent achievements in development of nanostructured
dispersions and biocolloids for drug delivery applications. We emphasize the key role of …

Cubosomes and hexosomes as novel nanocarriers for bioactive compounds

C Tan, SF Hosseini, SM Jafari - Journal of Agricultural and Food …, 2022 - ACS Publications
Cubosomes and hexosomes are nanostructured liquid crystalline particles, known as
biocompatible nanocarriers for drug delivery. In recent years, there has been good interest …

A comprehensive overview of dry powder inhalers for pulmonary drug delivery: Challenges, advances, optimization techniques, and applications

HI Shahin, L Chablani - Journal of Drug Delivery Science and Technology, 2023 - Elsevier
Dry powder inhaler (DPI) is an attractive dosage form for local and systemic pulmonary drug
delivery. However, designing DPIs with adequate physicochemical properties is …

Lipid-based nanocarriers for neurological disorders: a review of the state-of-the-art and therapeutic success to date

BA Witika, MS Poka, PH Demana, SK Matafwali… - Pharmaceutics, 2022 - mdpi.com
Neurodegenerative disorders including Alzheimer's, Parkinson's, and dementia are chronic
and advanced diseases that are associated with loss of neurons and other related …

Lipid-based liquid crystals as carriers for antimicrobial peptides: phase behavior and antimicrobial effect

L Boge, H Bysell, L Ringstad, D Wennman, A Umerska… - Langmuir, 2016 - ACS Publications
The number of antibiotic-resistant bacteria is increasing worldwide, and the demand for
novel antimicrobials is constantly growing. Antimicrobial peptides (AMPs) could be an …

Smart polymeric micelles for anticancer hydrophobic drugs

A Guzmán Rodríguez, M Sablón Carrazana… - Cancers, 2022 - mdpi.com
Simple Summary Cancer has been a lethal and high-incidence disease for many years and
its cure is characterized by invasive methods and with notable side effects. Nanotechnology …