Measuring the elastic modulus of soft culture surfaces and three-dimensional hydrogels using atomic force microscopy

MDA Norman, SA Ferreira, GM Jowett, L Bozec… - Nature …, 2021 - nature.com
Growing interest in exploring mechanically mediated biological phenomena has resulted in
cell culture substrates and 3D matrices with variable stiffnesses becoming standard tools in …

A tense situation: forcing tumour progression

DT Butcher, T Alliston, VM Weaver - Nature Reviews Cancer, 2009 - nature.com
Cells within tissues are continuously exposed to physical forces including hydrostatic
pressure, shear stress, and compression and tension forces. Cells dynamically adapt to …

Elastic modulus determination of normal and glaucomatous human trabecular meshwork

JA Last, T Pan, Y Ding, CM Reilly… - … & visual science, 2011 - iovs.arvojournals.org
Purpose.: Elevated intraocular pressure (IOP) is a risk factor for glaucoma. The principal
outflow pathway for aqueous humor in the human eye is through the trabecular meshwork …

Selenium reduces cadmium uptake into rice suspension cells by regulating the expression of lignin synthesis and cadmium-related genes

J Cui, T Liu, Y Li, F Li - Science of the total environment, 2018 - Elsevier
Although previous studies have indicated that selenium (Se) can reduce cadmium (Cd)
uptake into rice, the mechanism at the cellular level has not been reported. Here, rice …

The effect of the endothelial cell cortex on atomic force microscopy measurements

R Vargas-Pinto, H Gong, A Vahabikashi, M Johnson - Biophysical journal, 2013 - cell.com
We examined whether the presence of the cell cortex might explain, in part, why previous
studies using atomic force microscopy (AFM) to measure cell modulus (E) gave higher …

Compliance profile of the human cornea as measured by atomic force microscopy

JA Last, SM Thomasy, CR Croasdale, P Russell… - Micron, 2012 - Elsevier
The ability to accurately determine the elastic modulus of each layer of the human cornea is
a crucial step in the design of better corneal prosthetics. In addition, knowledge of the elastic …

Increased stiffness and flow resistance of the inner wall of Schlemm's canal in glaucomatous human eyes

A Vahabikashi, A Gelman, B Dong… - Proceedings of the …, 2019 - National Acad Sciences
The cause of the elevated outflow resistance and consequent ocular hypertension
characteristic of glaucoma is unknown. To investigate possible causes for this flow …

Rolling of soft microbots with tunable traction

Y Gao, B Sprinkle, E Springer, DWM Marr, N Wu - Science Advances, 2023 - science.org
Microbot (μbot)–based targeted drug delivery has attracted increasing attention due to its
potential for avoiding side effects associated with systemic delivery. To date, most μbots are …

Indenting soft samples (hydrogels and cells) with cantilevers possessing various shapes of probing tip

J Zemła, J Bobrowska, A Kubiak, T Zieliński… - European Biophysics …, 2020 - Springer
The identification of cancer-related changes in cells and tissues based on the
measurements of elastic properties using atomic force microscopy (AFM) seems to be …

The applications of atomic force microscopy to vision science

JA Last, P Russell, PF Nealey… - … ophthalmology & visual …, 2010 - iovs.arvojournals.org
The atomic force microscope (AFM) is widely used in materials science and has found many
applications in biological sciences but has been limited in use in vision science. The AFM …