Recent advances in microscale electroporation
Electroporation (EP) is a commonly used strategy to increase cell permeability for
intracellular cargo delivery or irreversible cell membrane disruption using electric fields. In …
intracellular cargo delivery or irreversible cell membrane disruption using electric fields. In …
An atlas of nano-enabled neural interfaces
H Acarón Ledesma, X Li, JL Carvalho-de-Souza… - Nature …, 2019 - nature.com
Advances in microscopy and molecular strategies have allowed researchers to gain insight
into the intricate organization of the mammalian brain and the roles that neurons play in …
into the intricate organization of the mammalian brain and the roles that neurons play in …
Targeted extracellular vesicle delivery systems employing superparamagnetic iron oxide nanoparticles
Z Zhuo, J Wang, Y Luo, R Zeng, C Zhang, W Zhou… - Acta biomaterialia, 2021 - Elsevier
In the past decade, the study of extracellular vesicles (EVs), especially exosomes (50–150
nm) have attracted growing interest in numerous areas of cancer and tissue regeneration …
nm) have attracted growing interest in numerous areas of cancer and tissue regeneration …
Bulk electroporation for intracellular delivery directly driven by mechanical stimulus
Electroporation (EP) is an effective and widely accepted intracellular delivery method for
fundamental research and medical applications. Existing electroporation methods usually …
fundamental research and medical applications. Existing electroporation methods usually …
[HTML][HTML] In situ sensors for blood-brain barrier (BBB) on a chip
The blood-brain barrier (BBB) is critical for the central nervous system, as its integrity
protects neurons and other brain cells from harmful toxicants and disease-associated …
protects neurons and other brain cells from harmful toxicants and disease-associated …
Electrotherapies for glioblastoma
Abstract Non‐thermal, intermediate frequency (100–500 kHz) electrotherapies present a
unique therapeutic strategy to treat malignant neoplasms. Here, pulsed electric fields (PEFs) …
unique therapeutic strategy to treat malignant neoplasms. Here, pulsed electric fields (PEFs) …
Dynamic 3D on-chip BBB model design, development, and applications in neurological diseases
The blood–brain barrier (BBB) is a vital structure for maintaining homeostasis between the
blood and the brain in the central nervous system (CNS). Biomolecule exchange, ion …
blood and the brain in the central nervous system (CNS). Biomolecule exchange, ion …
New potential strategies for Alzheimer's disease prevention: pegylated biodegradable dexibuprofen nanospheres administration to APPswe/PS1dE9
E Sánchez-López, M Ettcheto, MA Egea… - … , Biology and Medicine, 2017 - Elsevier
Dexibuprofen loaded pegylated poly (lactic-co-glycolic) nanospheres prepared by solvent
diffusion method were designed to increase Dexibuprofen brain delivery reducing systemic …
diffusion method were designed to increase Dexibuprofen brain delivery reducing systemic …
Tumor-derived extracellular vesicles disrupt the blood–brain barrier endothelium following high-frequency irreversible electroporation
KR Murphy, KN Aycock, S Marsh, AN Hay… - Scientific Reports, 2024 - nature.com
High-frequency irreversible electroporation (H-FIRE), a nonthermal brain tumor ablation
therapeutic, generates a central tumor ablation zone while transiently disrupting the …
therapeutic, generates a central tumor ablation zone while transiently disrupting the …
Predictive therapeutic planning for irreversible electroporation treatment of spontaneous malignant glioma
Purpose Irreversible electroporation (IRE) has been developed as a promising minimally
invasive treatment to ablate spontaneous brain tumors with pulsed electric fields in canine …
invasive treatment to ablate spontaneous brain tumors with pulsed electric fields in canine …