Sodium–glucose cotransporter type 2 inhibitors for the treatment of type 2 diabetes mellitus
AJ Scheen - Nature reviews endocrinology, 2020 - nature.com
The management of type 2 diabetes mellitus (T2DM) is becoming increasingly complex.
Sodium–glucose cotransporter type 2 inhibitors (SGLT2is) are the newest antidiabetic …
Sodium–glucose cotransporter type 2 inhibitors (SGLT2is) are the newest antidiabetic …
European expert consensus on practical management of specific aspects of parathyroid disorders in adults and in pregnancy: recommendations of the ESE …
J Bollerslev, L Rejnmark, A Zahn, A Heck… - European journal of …, 2022 - academic.oup.com
This European expert consensus statement provides recommendations for the diagnosis
and management of primary hyperparathyroidism (PHPT), chronic hypoparathyroidism in …
and management of primary hyperparathyroidism (PHPT), chronic hypoparathyroidism in …
Renal and cardiovascular effects of SGLT2 inhibition in combination with loop diuretics in patients with type 2 diabetes and chronic heart failure: the RECEDE-CHF …
Background: SGLT2 (sodium-glucose cotransporter-2) inhibitors improve heart failure–
associated outcomes in patients with type 2 diabetes. In patients with heart failure, SGLT2 …
associated outcomes in patients with type 2 diabetes. In patients with heart failure, SGLT2 …
Kidney glycolysis serves as a mammalian phosphate sensor that maintains phosphate homeostasis
How phosphate levels are detected in mammals is unknown. The bone-derived hormone
fibroblast growth factor 23 (FGF23) lowers blood phosphate levels by reducing kidney …
fibroblast growth factor 23 (FGF23) lowers blood phosphate levels by reducing kidney …
A role for tubular Na+/H+ exchanger NHE3 in the natriuretic effect of the SGLT2 inhibitor empagliflozin
A Onishi, Y Fu, R Patel, M Darshi… - American Journal …, 2020 - journals.physiology.org
Inhibitors of proximal tubular Na+-glucose cotransporter 2 (SGLT2) are natriuretic, and they
lower blood pressure. There are reports that the activities of SGLT2 and Na+-H+ exchanger …
lower blood pressure. There are reports that the activities of SGLT2 and Na+-H+ exchanger …
Critical analysis of the effects of SGLT2 inhibitors on renal tubular sodium, water and chloride homeostasis and their role in influencing heart failure outcomes
M Packer, CS Wilcox, JM Testani - Circulation, 2023 - Am Heart Assoc
SGLT2 (sodium-glucose cotransporter 2) inhibitors interfere with the reabsorption of glucose
and sodium in the early proximal renal tubule, but the magnitude and duration of any …
and sodium in the early proximal renal tubule, but the magnitude and duration of any …
Natriuretic effect of two weeks of dapagliflozin treatment in patients with type 2 diabetes and preserved kidney function during standardized sodium intake: results of …
RA Scholtes, MHA Muskiet, MJB van Baar… - Diabetes …, 2021 - Am Diabetes Assoc
OBJECTIVE Sodium–glucose cotransporter 2 (SGLT2) inhibitors reduce the risk for heart
failure hospitalization potentially by inducing sodium excretion, osmotic diuresis, and …
failure hospitalization potentially by inducing sodium excretion, osmotic diuresis, and …
Physical activity-dependent regulation of parathyroid hormone and calcium-phosphorous metabolism
G Lombardi, E Ziemann, G Banfi… - International journal of …, 2020 - mdpi.com
Exercise perturbs homeostasis, alters the levels of circulating mediators and hormones, and
increases the demand by skeletal muscles and other vital organs for energy substrates …
increases the demand by skeletal muscles and other vital organs for energy substrates …
Effects of GLP-1 agonists and SGLT2 inhibitors during pregnancy and lactation on offspring outcomes: a systematic review of the evidence
DRP Muller, DJ Stenvers, A Malekzadeh… - Frontiers in …, 2023 - frontiersin.org
Aims/hypothesis Glucagon-like peptide 1 (GLP-1) agonists and sodium-glucose co-
transporter-2 (SGLT2) inhibitors are novel drugs which have recently seen rapid uptake in …
transporter-2 (SGLT2) inhibitors are novel drugs which have recently seen rapid uptake in …
Kidney-protective effects of SGLT2 inhibitors
The sodium-glucose cotransporter 2 (SGLT2) inhibitors have become an integral part of
clinical practice guidelines to slow the progression of CKD in patients with and without …
clinical practice guidelines to slow the progression of CKD in patients with and without …