A guide to the composition and functions of the extracellular matrix
Extracellular matrix (ECM) is a dynamic 3‐dimensional network of macromolecules that
provides structural support for the cells and tissues. Accumulated knowledge clearly …
provides structural support for the cells and tissues. Accumulated knowledge clearly …
A comprehensive review on collagen type I development of biomaterials for tissue engineering: From biosynthesis to bioscaffold
Collagen is the most abundant structural protein found in humans and mammals, particularly
in the extracellular matrix (ECM). Its primary function is to hold the body together. The …
in the extracellular matrix (ECM). Its primary function is to hold the body together. The …
Memorable full-color circularly polarized luminescence from chiral co-assembled polymer films enabled by multipath transfer
The modulation of circularly polarized luminescence (CPL) is of importance for display and
asymmetric chemical synthesis. However, the underlying mechanism of CPL transfer …
asymmetric chemical synthesis. However, the underlying mechanism of CPL transfer …
Cartilage-related collagens in osteoarthritis and rheumatoid arthritis: from pathogenesis to therapeutics
Z Ouyang, L Dong, F Yao, K Wang, Y Chen… - International Journal of …, 2023 - mdpi.com
Collagens serve essential mechanical functions throughout the body, particularly in the
connective tissues. In articular cartilage, collagens provide most of the biomechanical …
connective tissues. In articular cartilage, collagens provide most of the biomechanical …
Collagen-based biocomposites inspired by bone hierarchical structures for advanced bone regeneration: Ongoing research and perspectives
D Qin, N Wang, XG You, AD Zhang, XG Chen… - Biomaterials …, 2022 - pubs.rsc.org
Bone is a hard-connective tissue composed of matrix, cells and bioactive factors with a
hierarchical structure, where the matrix is mainly composed of type I collagen and …
hierarchical structure, where the matrix is mainly composed of type I collagen and …
[HTML][HTML] Multivalent protein-drug conjugates–An emerging strategy for the upgraded precision and efficiency of drug delivery to cancer cells
N Porębska, K Ciura, A Chorążewska… - Biotechnology …, 2023 - Elsevier
With almost 20 million new cases per year, cancer constitutes one of the most important
challenges for public health systems. Unlike traditional chemotherapy, targeted anti-cancer …
challenges for public health systems. Unlike traditional chemotherapy, targeted anti-cancer …
Collagen biosynthesis, processing, and maturation in lung ageing
C Onursal, E Dick, I Angelidis, HB Schiller… - Frontiers in …, 2021 - frontiersin.org
In addition to providing a macromolecular scaffold, the extracellular matrix (ECM) is a critical
regulator of cell function by virtue of specific physical, biochemical, and mechanical …
regulator of cell function by virtue of specific physical, biochemical, and mechanical …
Collagen-based hydrogels for the eye: A comprehensive review
Collagen-based hydrogels have emerged as a highly promising platform for diverse
applications in ophthalmology, spanning from drug delivery systems to biomedical …
applications in ophthalmology, spanning from drug delivery systems to biomedical …
Tunnels for protein export from the endoplasmic reticulum
I Raote, V Malhotra - Annual review of biochemistry, 2021 - annualreviews.org
The functions of coat protein complex II (COPII) coats in cargo packaging and the creation of
vesicles at the endoplasmic reticulum are conserved in eukaryotic protein secretion …
vesicles at the endoplasmic reticulum are conserved in eukaryotic protein secretion …
Natural load-bearing protein materials
MJ Harrington, P Fratzl - Progress in Materials Science, 2021 - Elsevier
Biological tissues in animals generally consist an extracellular matrix often with cells
embedded in it. These materials are primarily comprised of different protein building blocks …
embedded in it. These materials are primarily comprised of different protein building blocks …