The transient receptor potential ankyrin 1 (TRPA1) channel is a non-selective cation channel
that senses irritant chemicals. Its activation is closely associated with pain, inflammation, and …

In addition to the sense of taste and olfaction, chemesthesis, the sensation of irritation,
pungency, cooling, warmth, or burning elicited by spices and herbs, plays a central role in …

The ion channel TRPA1 is a promiscuous chemosensor, with reported response to a wide
spectrum of noxious electrophilic irritants, as well as cold, heat, and mechanosensation. It is …

The perception of pungency can be attributed to the combination of pain and heat, and it has
critical impacts on food flavor and food consumption preferences. Many studies have …

In both developed and emerging economies, carcinoma is one of the most frequent
malignancies. Non-small cell lung cancer accounts for 80% of all melanoma within India …

Breast cancer is becoming the leading risk factor for death, affecting millions of women.
hormone gene expression in living organisms, which may lead to the improvement and …

Transient receptor potential (TRP) channels, first identified in Drosophila in 1969, are
multifunctional ion channels expressed in various cell types. Structurally, TRP channels …

Abstract Transient Receptor Potential Ankyrin 1 (TRPA1), which is expressed in the airways,
has causative and exacerbating roles in respiratory diseases. TRPA1 is known as a target of …

Background/objectives Topically applied antifungal agents can induce adverse effects, such
as pain and irritation. The transient receptor potential (TRP) channels—TRPA1 and TRPV1 …

Transient receptor potential cation channel subfamily A member 1 (TRPA1), a member of the
transient receptor potential family, detects a wide range of environmental stimuli, such as …