Mechanisms of environmental contributions to fatty liver disease

B Wahlang, J Jin, JI Beier, JE Hardesty, EF Daly… - Current environmental …, 2019 - Springer
Purpose Fatty liver disease (FLD) affects over 25% of the global population and may lead to
liver-related mortality due to cirrhosis and liver cancer. FLD caused by occupational and …

The connection of azole fungicides with xeno-sensing nuclear receptors, drug metabolism and hepatotoxicity

P Marx-Stoelting, C Knebel, A Braeuning - Cells, 2020 - mdpi.com
Azole fungicides, especially triazole compounds, are widely used in agriculture and as
pharmaceuticals. For a considerable number of agricultural azole fungicides, the liver has …

Amygdalin potentiates the anti-cancer effect of Sorafenib on Ehrlich ascites carcinoma and ameliorates the associated liver damage

AA Attia, AF Salama, JG Eldiasty, SAER Mosallam… - Scientific Reports, 2022 - nature.com
The burden of cancer diseases is increasing every year, therefore, the demands to figure out
novel drugs that can retain antitumor properties have been raised. This study aimed to …

[HTML][HTML] Melatonin improves therapeutic potential of mesenchymal stem cells-derived exosomes against renal ischemia-reperfusion injury in rats

FA Alzahrani - American journal of translational research, 2019 - ncbi.nlm.nih.gov
Renal ischemia-reperfusion injury (RIRI) is one of the main causes for acute kidney injury
(AKI). Many previous attempts failed to adopt a suitable treatment regimen for AKI. Recently …

[HTML][HTML] Tebuconazole induces liver injury coupled with ROS-mediated hepatic metabolism disorder

T Ku, M Zhou, Y Hou, Y Xie, G Li, N Sang - … and Environmental Safety, 2021 - Elsevier
Tebuconazole, the most widely used fungicide, is reported to cause various environmental
problems and have serious health risks in humans. Despite numerous advances in toxicity …

Bromuconazole exposure induces cardiotoxicity and lipid transport disorder in larval zebrafish

Z Qin, W Wang, Y Weng, Z Bao, G Yang… - … and Physiology Part C …, 2022 - Elsevier
Bromuconazole (BRO), as one of the typical triazole fungicides, has not been reported on its
effects on aquatic organisms. In this study, zebrafish embryos were used as experimental …

Chitosan nanoparticles from Artemia salina inhibit progression of hepatocellular carcinoma in vitro and in vivo

MM Elkeiy, AA Khamis, MM El-Gamal… - … Science and Pollution …, 2020 - Springer
This study was conducted to evaluate the effect of chitosan nanoparticles (CNPs) isolated
from Artemia salina against hepatocellular carcinoma (HCC) both in vitro (HepG2) and in …

Dietary propionic acid enhances antibacterial and immunomodulatory effects of oxytetracycline on Nile tilapia, Oreochromis niloticus

M El-Adawy, MA El-Aziz, K El-Shazly, NG Ali… - … science and pollution …, 2018 - Springer
This study was carried out to evaluate the potential antibacterial and immunomodulatory
effects of the dietary acidifier propionic acid (PA) when given alone or in combination with …

[HTML][HTML] Melatonin maximizes the therapeutic potential of non-preconditioned MSCs in a DEN-induced rat model of HCC

MA El-Magd, Y Mohamed, ES El-Shetry… - Biomedicine & …, 2019 - Elsevier
Pretreatment of mesenchymal stem cells (MSCs) with melatonin (Mel) improves their
potential therapeutic effect on chronic diseases and cancers. However, this preconditioning …

Impacts of florfenicol on immunity, antioxidant activity, and histopathology of Oreochromis niloticus: a potential protective effect of dietary spirulina platensis

NIS Abu-Zahra, MM Elseify, AA Atia… - Veterinary Research …, 2024 - Springer
The misuse of antibiotics enhances the development of resistant microorganisms and
decreases the efficacy of treatments. Florfenicol (FF) is one of the antibiotics approved for …