Spinal cord injury (SCI) leads to loss of motor and sensory function below the injury level
and imposes a considerable burden on patients, families, and society. Repair of the injured …

Traumatic spinal cord injury (SCI) has devastating consequences for the physical, social and
vocational well-being of patients. The demographic of SCIs is shifting such that an …

Spinal cord injury (SCI) can cause permanent loss of sensory and motor function, and there
is no effective clinical treatment, to date. Due to the complex pathological process involved …

Members of the metzincin family of metalloproteinases have long been considered merely
degradative enzymes for extracellular matrix molecules. Recently, however, there has been …

Brain and spinal cord injury can result in permanent cognitive, motor, sensory and
autonomic deficits. The central nervous system (CNS) has a poor intrinsic capacity for …

It has been 50years since Gross and Lapiere discovered collagenolytic activity during
tadpole tail metamorphosis, which was later on revealed as MMP-1, the founding member of …

purpose. In glaucoma, the optic nerve head (ONH) is the likely site of initial injury and
elevated intraocular pressure (IOP) is the best-known risk factor. This study determines …

The prospects of achieving regeneration in the central nervous system (CNS) have
changed, as most recent findings indicate that several species, including humans, can …

This article reviews stem cell-based strategies for spinal cord injury repair, and practical
issues concerning their translation to the clinic. Recent progress in the stem cell field …

Olfactory ensheathing glia (OEG) are a specialized type of glia that guide primary olfactory
axons from the neuroepithelium in the nasal cavity to the brain. The primary olfactory system …