Biological membranes are tricky to investigate. They are complex in terms of molecular
composition and structure, functional over a wide range of time scales, and characterized by …

In this review, we outline the growing role that molecular dynamics simulation is able to play
as a design tool in drug delivery. We cover both the pharmaceutical and computational …

Electrospun fibers are versatile biomaterial platforms with great potential to support
regeneration. Electrospun fiber characteristics such as fiber diameter, degree of alignment …

We review the use of molecular dynamics (MD) simulation as a drug design tool in the
context of the role that the lipid membrane can play in drug action, ie, the interaction …

In this study using phospholipids with high transition temperature and taking advantage of
PEGylation, we designed liposomal formulation targeted with folic acid (FA) to improve the …

Microfluidic enables precise control over the continuous mixing of fluid phases at the
micrometre scale, aiming to optimize the processing parameters and to facilitate scale-up …

The cell membrane is a restrictive biological barrier, especially for large, charged molecules,
such as proteins. The use of cell-penetrating peptides (CPPs) can facilitate the delivery of …

Since the first polyethylene glycol (PEG) ylated protein was approved by the FDA in 1990,
PEGylation has been successfully applied to develop drug delivery systems through …

Sterically stabilized liposomes (SSLs)(PEGylated liposomes) are applied as effective drug
delivery vehicles. Understanding the interactions between hydrophobic compounds and …

In this study, novel cupric-tirapazamine [Cu (TPZ) 2]-liposomes were developed as an
effective hypoxia-targeted therapeutic, which potentiated radiotherapy in a three …