Background Blood vessel segmentation is a topic of high interest in medical image analysis
since the analysis of vessels is crucial for diagnosis, treatment planning and execution, and …

This review provides the basic principle and rational for ROC analysis of rating and
continuous diagnostic test results versus a gold standard. Derived indexes of accuracy, in …

'Optimal cutpoints' for binary classification tasks are often established by testing which
cutpoint yields the best discrimination, for example the Youden index, in a specific sample …

Abstract The Spielberger State-Trait Anxiety Inventory (STAI) has been widely used to
measure the state and trait components of anxiety. We sought to develop a short, yet reliable …

Sensitivity and specificity are two components that measure the inherent validity of a
diagnostic test for dichotomous outcomes against a gold standard. Receiver operating …

Aim To develop a simple screening test to identify older adults at high risk for sarcopenia.
Methods We studied 1971 functionally independent, community‐dwelling adults aged 65 …

Abstract The Youden Index is a frequently used summary measure of the ROC (Receiver
Operating Characteristic) curve. It both, measures the effectiveness of a diagnostic marker …

The neural mechanisms that support naturalistic learning via effective pedagogical
approaches remain elusive. Here we used functional near-infrared spectroscopy to measure …

In this issue of the Journal, Auer and colleagues conclude that serum levels of neuron-
specific enolase (NSE), a biochemical marker of ischemic brain injury, may have clinical …

Recently developed corporate bankruptcy prediction models adopt a contingent claims
valuation approach. However, despite their theoretical appeal, tests of their performance …