Silymarin, an extract from milk thistle seeds, has been used for centuries to treat hepatic
conditions. Preclinical data indicate that silymarin can reduce oxidative stress and …

The flavonoid silymarin extracted from the seeds of Sylibum marianum is a mixture of 6
flavolignan isomers. The 3 more important isomers are silybin (or silibinin), silydianin, and …

В настоящем издании проанализированы и систематизированы сведения по
клиническому применению лекарственных средств, для которых гепатотропное …

Background Chemotherapeutic agents, with or without other drugs and radiation, may cause
indirect or direct hepatotoxicity. Doxorubicin-induced hepatotoxicity (DIH) is a major health …

For cancer therapy, the usefulness of mesoporous silica nanoparticles (MPSNPs) has been
widely discussed, likely due to its inorganic nature and excellent structural features. The …

Purpose Thus far, silymarin has been examined in several studies for prevention or
treatment of various chemotherapy or radiotherapy-induced adverse reactions. In this …

Liver diseases, encompassing conditions such as cirrhosis, present a substantial global
health challenge with diverse etiologies, including viral infections, alcohol consumption, and …

Background Breast cancer is one of the most common diseases globally that may have side
effects on liver and renal function. Pharmacological treatments to reduce adverse liver and …

Silymarin is a plant‑derived flavonoid which is extracted from the fruits and seeds of milk
thistle (Silybum marianum L. Gaertn.), which belongs to the family Asteraceae. 1 The extract …

This study investigated the effects of thymoquinone, silymarin, and N-acetylcysteine in a rat
model with carbon tetrachloride (CCl 4)-induced hepatotoxicity. Although numerous similar …