Schizophrenia is a disease of abnormal brain development. Considerable evidence now
indicates that environmental factors have a causative role in schizophrenia. Elevated …

The adult brain functions within a well-controlled stable environment, the properties of which
are determined by cellular exchange mechanisms superimposed on the diffusion restraint …

Neurogenesis must be properly regulated to ensure that cell production does not exceed the
requirements of the growing cerebral cortex, yet our understanding of mechanisms that …

Maternal inflammation during pregnancy affects placental function and is associated with
increased risk of neurodevelopmental disorders in the offspring. The molecular mechanisms …

Inflammation entails a complex set of defense mechanisms acting in concert to restore the
homeostatic balance in organisms after damage or pathogen invasion. This immune …

Prenatal exposure to infectious or inflammatory insults is increasingly recognized to
contribute to the etiology of psychiatric disorders with neurodevelopmental components …

Pediatric hydrocephalus, the leading reason for brain surgery in children, is characterized by
enlargement of the cerebral ventricles classically attributed to cerebrospinal fluid (CSF) …

Background The association between maternal infection and neurodevelopmental defects in
progeny is well established, although the biological mechanisms and the pathogenic …

Preterm brain injury, occurring in approximately 30% of infants born< 32 weeks gestational
age, is associated with an increased risk of neurodevelopmental disorders, such as autism …

The choroid plexus epithelium controls the movement of solutes between the blood and the
cerebrospinal fluid. It has been considered as a functionally more immature interface during …