Aestivation is considered to be one of the “purest” hypometabolic states in nature, as it
involves aerobic dormancy that can be induced and sustained without complex factors …

Long-duration space missions to Mars will impose extreme stresses of physical and
psychological nature on the crew, as well as significant logistical and technical challenges …

White-nose syndrome (WNS) in North American bats is caused by an invasive cutaneous
infection by the psychrophilic fungus Pseudogymnoascus destructans (Pd). We compared …

White-nose syndrome is a fungal disease killing bats in eastern North America, but disease
is not seen in European bats and is less severe in some North American species. We show …

In mammals, torpor/hibernation is a state that is characterized by an active reduction in
metabolic rate followed by a progressive decrease in body temperature. Torpor was …

White-nose syndrome (WNS) is a fungal disease responsible for decimating many bat
populations in North America. Pseudogymnoascus destructans (Pd), the psychrophilic …

Hibernation, the use of prolonged torpor to depress metabolism, is employed by mammals to
conserve resources during extended periods of extreme temperatures and/or resource …

Spinal cord injury is a serious disease of the central nervous system involving irreversible
nerve injury and various organ system injuries. At present, no effective clinical treatment …

Mammalian hibernators adapt to prolonged periods of immobility, hypometabolism,
hypothermia, and oxidative stress, each capable of reducing bone marrow activity. In this …

As microbial drug-resistance increases, there is a critical need for new classes of
compounds to combat infectious diseases. The Ixodes scapularis tick antifreeze …