Parvalbumin-positive neurons are the largest class of GABAergic, inhibitory neurons in the
central nervous system. In the cortex, these fast-spiking cells provide feedforward and …

Learning has been associated with modifications of synaptic and circuit properties, but the
precise changes storing information in mammals have remained largely unclear. We …

Although different regions of the brain are dedicated to specific functions, the intra-and inter-
regional heterogeneity of astrocytes and microglia in these regions has not yet been fully …

Recurrent cortical activity sculpts visual perception by refining, amplifying or suppressing
visual input. However, the rules that govern the influence of recurrent activity remain …

Importance Factors associated with synapse loss beyond amyloid-β plaques and
neurofibrillary tangles may more closely correlate with the emergence of cognitive deficits in …

The medial prefrontal cortex (mPFC) mediates a variety of complex cognitive functions via its
vast and diverse connections with cortical and subcortical structures. Understanding the …

Two-photon voltage imaging has long been heralded as a transformative approach capable
of answering many long-standing questions in modern neuroscience. However, exploiting …

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The neural dynamics generating sensory, motor, and cognitive functions are commonly
understood through field theories for neural population activity. Classic neural field theories …

Two-photon, single-cell resolution optogenetics based on holographic light-targeting
approaches enables the generation of precise spatiotemporal neuronal activity patterns and …