[HTML][HTML] Repurposing anticancer drugs for the management of COVID-19
Since its outbreak in the last December, coronavirus disease 2019 (COVID-19) caused by
SARS-CoV-2 has rapidly spread worldwide at a pandemic proportion and thus is regarded …
SARS-CoV-2 has rapidly spread worldwide at a pandemic proportion and thus is regarded …
Gynecological cancer prognosis using machine learning techniques: A systematic review of the last three decades (1990–2022)
J Sheehy, H Rutledge, UR Acharya, HW Loh… - Artificial Intelligence in …, 2023 - Elsevier
Abstract Objective Many Computer Aided Prognostic (CAP) systems based on machine
learning techniques have been proposed in the field of oncology. The objective of this …
learning techniques have been proposed in the field of oncology. The objective of this …
Morusin induces paraptosis-like cell death through mitochondrial calcium overload and dysfunction in epithelial ovarian cancer
J Xue, R Li, X Zhao, C Ma, X Lv, L Liu, P Liu - Chemico-biological …, 2018 - Elsevier
Epithelial ovarian cancer (EOC) is the leading cause of death among all gynecological
cancers. Morusin, a prenylated flavonoid extracted from the root bark of Morus australis, has …
cancers. Morusin, a prenylated flavonoid extracted from the root bark of Morus australis, has …
Decoding colorectal cancer epigenomics
Highlights•Epigenetic alterations are an emerging factor in colorectal carcinogenesis.•The
discovery of epigenetic pathways constitutes a major advance in cancer biomarker …
discovery of epigenetic pathways constitutes a major advance in cancer biomarker …
EIF5A2 enhances stemness of epithelial ovarian cancer cells via a E2F1/KLF4 axis
K Wang, Y Wang, Y Wang, S Liu, C Wang… - Stem Cell Research & …, 2021 - Springer
Background Ovarian cancer stem cells (OCSC), endowed with tumor-initiating and self-
renewal capacity, would account not only for the tumor growth, the peritoneal metastasis …
renewal capacity, would account not only for the tumor growth, the peritoneal metastasis …
Potential drug development and therapeutic approaches for clinical intervention in COVID-19
While the vaccination is now available to many countries and will slowly dissipate to others,
effective therapeutics for COVID-19 is still illusive. The SARS-CoV-2 pandemic has posed …
effective therapeutics for COVID-19 is still illusive. The SARS-CoV-2 pandemic has posed …
S100A10 and cancer hallmarks: structure, functions, and its emerging role in ovarian cancer
S100A10, which is also known as p11, is located in the plasma membrane and forms a
heterotetramer with annexin A2. The heterotetramer, comprising of two subunits of annexin …
heterotetramer with annexin A2. The heterotetramer, comprising of two subunits of annexin …
[HTML][HTML] The arrival of predictive biomarkers for monitoring therapy response to natural compounds in cancer drug discovery
Intrinsic or acquired drug resistance, adverse drug reactions and tumor heterogeneity
between and within cancer patients limit the efficacy of clinical management of advanced …
between and within cancer patients limit the efficacy of clinical management of advanced …
Revisiting antibody-drug conjugates and their predictive biomarkers in platinum-resistant ovarian cancer
K El Bairi, O Al Jarroudi, S Afqir - Seminars in Cancer Biology, 2021 - Elsevier
Until to date, platinum derived drugs are still the backbone of treating ovarian cancer (OC).
Most patients treated with platinum-based chemotherapy develop resistance during the …
Most patients treated with platinum-based chemotherapy develop resistance during the …
CCNG1 (Cyclin G1) regulation by mutant‐P53 via induction of Notch3 expression promotes high‐grade serous ovarian cancer (HGSOC) tumorigenesis and …
Y Xu, Q Zhang, C Miao, S Dongol, Y Li, C Jin… - Cancer …, 2019 - Wiley Online Library
TP53 mutation is considerably common in advanced high‐grade serous ovarian cancer
(HGSOC) and significantly associated with a poor prognosis. In this study, we investigated …
(HGSOC) and significantly associated with a poor prognosis. In this study, we investigated …