A review of reward processing and motivational impairment in schizophrenia

GP Strauss, JA Waltz, JM Gold - Schizophrenia bulletin, 2014 - academic.oup.com
This article reviews and synthesizes research on reward processing in schizophrenia, which
has begun to provide important insights into the cognitive and neural mechanisms …

The motivation and pleasure dimension of negative symptoms: neural substrates and behavioral outputs

AM Kring, DM Barch - European Neuropsychopharmacology, 2014 - Elsevier
A range of emotional and motivation impairments have long been clinically documented in
people with schizophrenia, and there has been a resurgence of interest in understanding …

The anticipation and outcome phases of reward and loss processing: A neuroimaging meta‐analysis of the monetary incentive delay task

S Oldham, C Murawski, A Fornito… - Human brain …, 2018 - Wiley Online Library
The processing of rewards and losses are crucial to everyday functioning. Considerable
interest has been attached to investigating the anticipation and outcome phases of reward …

Ventral striatal activation during reward processing in psychosis: a neurofunctional meta-analysis

J Radua, A Schmidt, S Borgwardt, A Heinz… - JAMA …, 2015 - jamanetwork.com
Importance Abnormal reward processing is suggested to underlie the formation of psychotic
symptoms, likely driven by elevated ventral striatal (VS) dopamine levels. Functional …

[HTML][HTML] Negative symptoms of schizophrenia: clinical characteristics, pathophysiological substrates, experimental models and prospects for improved treatment

MJ Millan, K Fone, T Steckler, WP Horan - European …, 2014 - Elsevier
Schizophrenia is a complex and multifactorial disorder generally diagnosed in young adults
at the time of the first psychotic episode of delusions and hallucinations. These positive …

Expected value and prediction error abnormalities in depression and schizophrenia

VB Gradin, P Kumar, G Waiter, T Ahearn, C Stickle… - Brain, 2011 - academic.oup.com
The dopamine system has been linked to anhedonia in depression and both the positive
and negative symptoms of schizophrenia, but it remains unclear how dopamine dysfunction …

Anhedonia in schizophrenia: distinctions between anticipatory and consummatory pleasure

DE Gard, AM Kring, MG Gard, WP Horan… - Schizophrenia research, 2007 - Elsevier
Research on anhedonia in schizophrenia has revealed mixed results, with patients reporting
greater anhedonia than healthy controls on self-report measures and semi-structured …

Reconceptualizing anhedonia: novel perspectives on balancing the pleasure networks in the human brain

K Rømer Thomsen, PC Whybrow… - Frontiers in behavioral …, 2015 - frontiersin.org
Anhedonia, the lack of pleasure, has been shown to be a critical feature of a range of
psychiatric disorders. Yet, it is currently measured primarily through subjective self-reports …

Goal representations and motivational drive in schizophrenia: the role of prefrontal–striatal interactions

DM Barch, EC Dowd - Schizophrenia bulletin, 2010 - academic.oup.com
The past several years have seen a resurgence of interest in understanding the
psychological and neural bases of what are often referred to as “negative symptoms” in …

Neural substrates of reward anticipation and outcome in schizophrenia: a meta-analysis of fMRI findings in the monetary incentive delay task

J Zeng, J Yan, H Cao, Y Su, Y Song, Y Luo… - Translational …, 2022 - nature.com
Dysfunction of the mesocorticolimbic dopaminergic reward system is a core feature of
schizophrenia (SZ), yet its precise contributions to different stages of reward processing and …