The epigenetic reader methyl-CpG-binding protein 2 (MeCP2) is an emerging oncogene in cancer biology
K Nejati-Koshki, CT Roberts, G Babaei, M Rastegar - Cancers, 2023 - mdpi.com
Simple Summary Methyl-CpG binding protein 2 (MeCP2) is a nuclear protein that is mainly
studied for its role as an epigenetic regulator of gene transcription. Gene mutations affecting …
studied for its role as an epigenetic regulator of gene transcription. Gene mutations affecting …
Current insights on extracellular vesicle-mediated glioblastoma progression: Implications in drug resistance and epithelial-mesenchymal transition
S Mukherjee, PP Pillai - Biochimica et Biophysica Acta (BBA)-General …, 2022 - Elsevier
Background Glioblastoma multiforme (GBM) is one of the most fatal tumors of the central
nervous system with high rate of disease progression, diagnosis, prognosis and low survival …
nervous system with high rate of disease progression, diagnosis, prognosis and low survival …
Integration of transcriptome and proteome profiles in placenta accreta reveals trophoblast over-migration as the underlying pathogenesis
N Li, R Hou, C Liu, T Yang, C Qiao, J Wei - Clinical Proteomics, 2021 - Springer
Background Placenta accreta (PA) is a major cause of maternal morbidity and mortality in
modern obstetrics, few studies have explored the underlying molecular mechanisms …
modern obstetrics, few studies have explored the underlying molecular mechanisms …
[HTML][HTML] Fibrogenic activity of MECP2 is regulated by phosphorylation in hepatic stellate cells
E Moran-Salvador, M Garcia-Macia, A Sivaharan… - Gastroenterology, 2019 - Elsevier
Background & Aims Methyl-CpG binding protein 2, MECP2, which binds to methylated
regions of DNA to regulate transcription, is expressed by hepatic stellate cells (HSCs) and is …
regions of DNA to regulate transcription, is expressed by hepatic stellate cells (HSCs) and is …
Role of PDGF-A-activated ERK signaling mediated FAK-paxillin interaction in oligodendrocyte progenitor cell migration
J Singh, K Sharma, EE Frost, PP Pillai - Journal of Molecular Neuroscience, 2019 - Springer
Oligodendrocyte progenitor cells (OPCs) originate from the sub-ventricular zone of the
developing brain. They migrate and proliferate to occupy the white matter tracts of the central …
developing brain. They migrate and proliferate to occupy the white matter tracts of the central …
[HTML][HTML] MECP2 promotes the migration and invasion of gastric cancer cells by modulating the Notch1/c-Myc/mTOR signaling pathways by suppressing FBXW7 …
L Zhao, X Wang, J Yang, Q Jiang, J Zhang… - American Journal of …, 2022 - ncbi.nlm.nih.gov
Abstract Methyl-CpG-binding protein 2 (MECP2), an epigenetic regulatory factor, promotes
the carcinogenesis and progression of a number of cancers. However, its role in the …
the carcinogenesis and progression of a number of cancers. However, its role in the …
[HTML][HTML] Cadmium induces A549 cell migration and invasion by activating ERK
H Zhai, T Pan, H Yang, H Wang… - Experimental and …, 2019 - spandidos-publications.com
Cadmium (Cd) is an established carcinogen that is involved in the progression of lung
cancer. However, the mechanisms underlying this Cd‑induced process have yet to be fully …
cancer. However, the mechanisms underlying this Cd‑induced process have yet to be fully …
Methyl-CpG Binding Protein 2 as a Potential Diagnostic and Prognostic Marker Facilitates Glioma Progression Through Activation of Wnt/β-Catenin Pathway
G Huang, Y Wu, Y Du, H Gan, S Hao - World Neurosurgery, 2023 - Elsevier
Background Glioma is the primary malignant tumor in the central nervous system and has
high malignancy, mortality, and recurrence rates. Because of its heterogeneity and drug …
high malignancy, mortality, and recurrence rates. Because of its heterogeneity and drug …
[HTML][HTML] Silencing miR-454 suppresses cell proliferation, migration and invasion via directly targeting MECP2 in renal cell carcinoma
H Liu, QL Liu, TS Zhai, J Lu, YZ Dong… - American journal of …, 2020 - ncbi.nlm.nih.gov
Renal cell cancer (RCC) is one of the most common malignant tumors of the urinary system.
MicroRNA-454 (miR-454) has been reported to play an important role in various cancer …
MicroRNA-454 (miR-454) has been reported to play an important role in various cancer …
MeCP2 differentially regulate the myelin MBP and PLP protein expression in oligodendrocytes and C6 glioma
K Sharma, J Singh, PP Pillai - Journal of molecular neuroscience, 2018 - Springer
MeCP2 (methyl-CpG binding protein 2), an epigenetic regulator, has been shown to
regulate the function of neurons and glial cells. Our previous study has demonstrated that …
regulate the function of neurons and glial cells. Our previous study has demonstrated that …