The gut microecological network is a complex microbial community within the human body
that plays a key role in linking dietary nutrition and host physiology. To understand the …

Advances in omics technologies have allowed spatially resolved molecular profiling of
single cells, providing a window not only into the diversity and distribution of cell types within …

Gene regulation plays a fundamental role in shaping tissue identity, function, and response
to perturbation. Regulatory processes are controlled by complex networks of interacting …

Inference and analysis of gene regulatory networks (GRNs) require software that integrates
multi-omic data from various sources. The Network Zoo (netZoo; netzoo. github. io) is a …

Multi-omics data integration is a term that refers to the process of combining and analyzing
data from different omic experimental sources, such as genomics, transcriptomics …

Gene regulatory networks (GRNs) are effective tools for inferring complex interactions
between molecules that regulate biological processes and hence can provide insights into …

Gaussian graphical models (GGMs) provide a framework for modeling conditional
dependencies in multivariate data. In this tutorial, we provide an overview of GGM theory …

Multi-omic approaches are expected to deliver a broader molecular view of cancer.
However, the promised mechanistic explanations have not quite settled yet. Here, we …

Motivation Systems biology analyses often use correlations in gene expression profiles to
infer co-expression networks that are then used as input for gene regulatory network …

Motivation Enzymatic reaction play a pivotal role in regulating cellular processes with a high
degree of specificity to biological functions. When enzymatic reactions are disrupted by …