The novel betacoronavirus, SARS-CoV-2 (severe acute respiratory syndrome coronavirus
2), has spread across the globe at an unprecedented rate since its first emergence in Wuhan …

The challenges of effective vaccination against influenza are gaining more mainstream
attention, as recent influenza seasons have reported low efficacy in annual vaccination …

In 2019, an 'influenza pandemic'and 'vaccine hesitancy'were listed as two of the top 10
challenges to global health by the WHO. The skin is a unique vaccination site, due to its …

There is an unmet public health need for a universal influenza vaccine (UIV) to provide
broad and durable protection from influenza virus infections. The identification of broadly …

Influenza remains one of the most significant public health threats due to its ability to cause
high morbidity and mortality worldwide. Although understanding of influenza viruses has …

Influenza viruses remain a constant burden in humans, causing millions of infections and
hundreds of thousands of deaths each year. Current influenza virus vaccine modalities …

The immunological and virological events that contribute to the establishment of Zika virus
(ZIKV) infection in humans are unclear. Here, we show that robust cellular innate immune …

Animal models have been an important tool for the development of influenza virus vaccines
since the 1940s. Over the past 80 years, influenza virus vaccines have evolved into more …

Vaccination is still the most efficient way to prevent an infection with influenza viruses.
Nevertheless, existing commercial vaccines face serious limitations such as availability …

Current flu vaccines rely on the induction of strain-specific neutralizing antibodies, which
leaves the population vulnerable to drifted seasonal or newly emerged pandemic strains …