Wnt signaling in brain tumors: A challenging therapeutic target

L Manfreda, E Rampazzo, L Persano - Biology, 2023 - mdpi.com
Simple Summary Wnt signaling is one of the main evolutionarily conserved developmental
pathways needed to instruct embryo formation and maintenance of organ tissues. Decades …

Multitargeted polypharmacotherapy for cancer treatment. theoretical concepts and proposals

A Duenas-Gonzalez, A Gonzalez-Fierro… - Expert Review of …, 2024 - Taylor & Francis
Introduction The pharmacological treatment of cancer has evolved from cytotoxic to
molecular targeted therapy. The median survival gains of 124 drugs approved by the FDA …