BACKGROUND Recurrent miscarriage and pre-eclampsia are common reproductive
disorders, but their causes are often unknown. Recent evidence has provided new insight …

Miscarriage and pre-eclampsia are the most common disorders of human pregnancy. Both
are placental-related and exceptional in other mammalian species. Ultrasound imaging has …

Signaling from endosomes is emerging as a mechanism by which selected receptors
provide sustained signals distinct from those generated at the plasma membrane. The …

Human leukocyte antigen-G (HLA-G) is a nonclassical HLA class-I molecule that was found
to be expressed by placental trophoblast cells 20 years ago. Because trophoblast forms the …

Normal pregnancy is considered as a Th2 type immunological state that favors an immune-
tolerance environment in order to prevent fetal rejection. Preeclampsia (PE) has been …

Establishing and maintaining maternal‐fetal tolerance is essential for a successful
pregnancy; failure of immunological adaptation to pregnancy leads to severe complications …

Human leukocyte antigen-G (HLA-G) is a non-classical class I HLA molecule that is
expressed by extravillous cytotrophoblast cells. This protein may play a critical role in the …

BACKGROUND: The aim of this study was to determine whether DNA-associated micro-
particles (MPs) in maternal plasma express fetal-derived human leukocyte antigen-G (HLA …

Systemic lupus erythematosus (SLE) is an autoimmune disease mainly mediated by the
deposit of immune complexes and defects in T lymphocytes and antigen‐presenting cells …

Despite decades of research, the highly prevalent pregnancy complication
preeclampsia,“the disease of theories,” has remained an enigma. Indeed, the etiology of …