[HTML][HTML] Small extracellular vesicles in cancer

K Abhange, A Makler, Y Wen, N Ramnauth, W Mao… - Bioactive Materials, 2021 - Elsevier
Extracellular vesicles (EV) are lipid-bilayer enclosed vesicles in submicron size that are
released from cells. A variety of molecules, including proteins, DNA fragments, RNAs, lipids …

Non-coding RNAs and exosomes: their role in the pathogenesis of sepsis

SMR Hashemian, MH Pourhanifeh, S Fadaei… - … Therapy-Nucleic Acids, 2020 - cell.com
Sepsis is characterized as an uncontrolled host response to infection, and it represents a
serious health challenge, causing excess mortality and morbidity worldwide. The discovery …

Genome-wide DNA hypermethylation opposes healing in patients with chronic wounds by impairing epithelial-mesenchymal transition

K Singh, Y Rustagi, AS Abouhashem… - The Journal of …, 2022 - Am Soc Clin Investig
An extreme chronic wound tissue microenvironment causes epigenetic gene silencing. An
unbiased whole-genome methylome was studied in the wound-edge tissue of patients with …

Extracellular vesicles: A double-edged sword in sepsis

M Burgelman, C Vandendriessche… - Pharmaceuticals, 2021 - mdpi.com
Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host
response to an infection. Several studies on mouse and patient sepsis samples have …

Toward integrated molecular lateral flow diagnostic tests using advanced micro-and nanotechnology

A Rubio-Monterde, D Quesada-González… - Analytical …, 2022 - ACS Publications
Since the COVID-19 pandemic, some of the routine methods for clinical diagnosis of
infectious diseases have become closer to the general population and terms like …

Extracellular vesicles: a new frontier for research in acute respiratory distress syndrome

RY Mahida, S Matsumoto… - American journal of …, 2020 - atsjournals.org
Recent research on extracellular vesicles (EVs) has provided new insights into
pathogenesis and potential therapeutic options for acute respiratory distress syndrome …

Extracellular vesicles participate in the pathogenesis of sepsis

C Tian, K Wang, M Zhao, S Cong, X Di… - Frontiers in Cellular and …, 2022 - frontiersin.org
Sepsis is one of the leading causes of mortality worldwide and is defined as life-threatening
organ dysfunction caused by a dysregulated host response to infection. The early diagnosis …

Regenerative potential of injured spinal cord in the light of epigenetic regulation and modulation

S Gupta, S Dutta, SP Hui - Cells, 2023 - mdpi.com
A spinal cord injury is a form of physical harm imposed on the spinal cord that causes
disability and, in many cases, leads to permanent mammalian paralysis, which causes a …

Advances and challenges in sepsis management: modern tools and future directions

E Santacroce, M D'Angerio, AL Ciobanu, L Masini… - Cells, 2024 - mdpi.com
Sepsis, a critical condition marked by systemic inflammation, profoundly impacts both innate
and adaptive immunity, often resulting in lymphopenia. This immune alteration can spare …

Epigenetic regulation of pulmonary inflammation

S Ahmad, XL Zhang, A Ahmad - Seminars in cell & developmental biology, 2024 - Elsevier
Pulmonary disease such as chronic obstructive pulmonary disease (COPD), asthma,
pulmonary fibrosis and pulmonary hypertension are the leading cause of deaths. More …