Multifunctional materials for implantable and wearable photonic healthcare devices

GH Lee, H Moon, H Kim, GH Lee, W Kwon… - Nature Reviews …, 2020 - nature.com
Numerous light-based diagnostic and therapeutic devices are routinely used in the clinic.
These devices have a familiar look as items plugged in the wall or placed at patients' …

1001 lights: luciferins, luciferases, their mechanisms of action and applications in chemical analysis, biology and medicine

ZM Kaskova, AS Tsarkova, IV Yampolsky - Chemical Society Reviews, 2016 - pubs.rsc.org
Bioluminescence (BL) is a spectacular phenomenon involving light emission by live
organisms. It is caused by the oxidation of a small organic molecule, luciferin, with molecular …

In vivo molecular bioluminescence imaging: new tools and applications

L Mezzanotte, M van't Root, H Karatas, EA Goun… - Trends in …, 2017 - cell.com
in vivo bioluminescence imaging (BLi) is an optical molecular imaging technique used to
visualize molecular and cellular processes in health and diseases and to follow the fate of …

Brightening up Biology: Advances in Luciferase Systems for in Vivo Imaging

S Liu, Y Su, MZ Lin, JA Ronald - ACS chemical biology, 2021 - ACS Publications
Bioluminescence imaging (BLI) using luciferase reporters is an indispensable method for
the noninvasive visualization of cell populations and biochemical events in living animals …

Development and applications of bioluminescent and chemiluminescent reporters and biosensors

HW Yeh, HW Ai - Annual Review of Analytical Chemistry, 2019 - annualreviews.org
Although fluorescent reporters and biosensors have become indispensable tools in
biological and biomedical fields, fluorescence measurements require external excitation …

Patient-derived glioma models: from patients to dish to animals

CC da Hora, MW Schweiger, T Wurdinger, BA Tannous - Cells, 2019 - mdpi.com
Glioblastoma (GBM) is the most common and malignant primary brain tumor in adults
associated with a poor survival. Current standard of care consists of surgical resection …

[HTML][HTML] Chemiluminescence and bioluminescence imaging for biosensing and therapy: in vitro and in vivo perspectives

Y Yan, P Shi, W Song, S Bi - Theranostics, 2019 - ncbi.nlm.nih.gov
Chemiluminescence (CL) and bioluminescence (BL) imaging technologies, which require
no external light source so as to avoid the photobleaching, background interference and …

[HTML][HTML] Tle4 controls both developmental acquisition and early post-natal maturation of corticothalamic projection neuron identity

MJ Galazo, DA Sweetser, JD Macklis - Cell reports, 2023 - cell.com
Identities of distinct neuron subtypes are specified during embryonic development, then
maintained during post-natal maturation. In cerebral cortex, mechanisms controlling early …

Modeling human carcinomas: physiologically relevant 3D models to improve anti-cancer drug development

C Unger, N Kramer, A Walzl, M Scherzer… - Advanced drug delivery …, 2014 - Elsevier
Anti-cancer drug development is inefficient, mostly due to lack of efficacy in human patients.
The high fail rate is partly due to the lack of predictive models or the inadequate use of …

An NIR‐II Fluorescence/Dual Bioluminescence Multiplexed Imaging for In Vivo Visualizing the Location, Survival, and Differentiation of Transplanted Stem Cells

D Huang, S Lin, Q Wang, Y Zhang, C Li… - Advanced Functional …, 2019 - Wiley Online Library
The in vivo distribution, viability, and differentiation capability of transplanted stem cells are
vital for the therapeutic efficacy of stem cell–based therapy. Herein, an NIR‐II …