Endothelial cells (ECs) are more than inert blood vessel lining material. Instead, they are
active players in the formation of new blood vessels (angiogenesis) both in health and (life …

Mesenchymal stem cells (MSCs) are multipotent cells capable of self-renewal and
differentiation. There is increasing evidence of the therapeutic value of MSCs in various …

Regenerative medicine is extensively interested in developing cell therapies using
mesenchymal stem cells (MSCs), with applications to several aging-associated diseases …

Background: Podocyte biology is a developing science that promises to help improve
understanding of the mechanistic nature of multiple diseases associated with proteinuria …

The metastatic process, ie the dissemination of cancer cells throughout the body to seed
secondary tumors at distant sites, requires cancer cells to leave the primary tumor and to …

Numerous physiological and pathological stimuli promote the rearrangement of the actin
cytoskeleton, thereby modulating cellular motile functions. Although it seems intuitively …

Dendritic spines are small actin-rich protrusions from neuronal dendrites that form the
postsynaptic part of most excitatory synapses and are major sites of information processing …

Directed cell migration is a physical process that requires dramatic changes in cell shape
and adhesion to the extracellular matrix. For efficient movement, these processes must be …

Cells receive extracellular stimuli in various ways: in the form of soluble molecules (growth
factors, cytokines and hormones) that interact with cell-surface receptors; from adhesive …

There is an accumulation of evidence in the literature demonstrating the integral role of
vimentin intermediate filaments (IFs) in the progression of lung cancers. Vimentin IF proteins …