Carbon ion therapy: a modern review of an emerging technology

TD Malouff, A Mahajan, S Krishnan, C Beltran… - Frontiers in …, 2020 - frontiersin.org
Radiation therapy is one of the most widely used therapies for malignancies. The
therapeutic use of heavy ions, such as carbon, has gained significant interest due to …

Roadmap: helium ion therapy

A Mairani, S Mein, E Blakely, J Debus… - Physics in Medicine …, 2022 - iopscience.iop.org
Helium ion beam therapy for the treatment of cancer was one of several developed and
studied particle treatments in the 1950s, leading to clinical trials beginning in 1975 at the …

A review on lymphocyte radiosensitivity and its impact on radiotherapy

H Paganetti - Frontiers in Oncology, 2023 - frontiersin.org
It is well known that radiation therapy causes lymphopenia in patients and that this is
correlated with a negative outcome. The mechanism is not well understood because …

Biological mechanisms to reduce radioresistance and increase the efficacy of radiotherapy: state of the art

F Busato, BE Khouzai, M Mognato - International journal of molecular …, 2022 - mdpi.com
Cancer treatment with ionizing radiation (IR) is a well-established and effective clinical
method to fight different types of tumors and is a palliative treatment to cure metastatic …

Radiation-induced degradation of silicon carbide MOSFETs–A review

T Baba, NA Siddiqui, NB Saidin, SHM Yusoff… - Materials Science and …, 2024 - Elsevier
Abstract Silicon Carbide (SiC) Metal-Oxide-Semiconductor Field-Effect Transistors
(MOSFETs) have gained significant attention due to their ability to achieve lower on …

The role of hypoxia and radiation in developing a CTCs-like phenotype in murine osteosarcoma cells

M Quartieri, A Puspitasari, T Vitacchio… - Frontiers in Cell and …, 2023 - frontiersin.org
Introduction: Cancer treatment has evolved significantly, yet concerns about tumor
recurrence and metastasis persist. Within the dynamic tumor microenvironment, a …

[HTML][HTML] Carbon ion (12C6+) irradiation induces the expression of Klrk1 in lung cancer and optimizes the tumor microenvironment based on the NKG2D/NKG2D-Ls …

J Wang, Z Dai, Y Miao, T Zhao, J Gan, C Zhao, J Ran… - Cancer Letters, 2021 - Elsevier
With the identification of “negative immune regulation” defects in the immune system and the
continuous improvement of immunotherapy, natural killer cells (NK) have received more …

[HTML][HTML] Basic and translational research on carbon-ion radiobiology

S Sai, M Koto, S Yamada - American Journal of Cancer Research, 2023 - ncbi.nlm.nih.gov
Carbon-ion beam irradiation (IR) has evident advantages over the conventional photon
beams in treating tumors. It releases enormous amount of energy in a well-defined range …

The role of particle therapy in adenoid cystic carcinoma and mucosal melanoma of the head and neck

DK Ebner, TD Malouff, SJ Frank… - International Journal of …, 2021 - meridian.allenpress.com
Particle irradiation is suitable for resistant histologies owing to a combination of improved
dose delivery with potential radiobiologic advantages in high linear energy transfer …

Smart radiotherapy biomaterials for image-guided in situ cancer vaccination

V Ainsworth, M Moreau, R Guthier, Y Zegeye… - Nanomaterials, 2023 - mdpi.com
Recent studies have highlighted the potential of smart radiotherapy biomaterials (SRBs) for
combining radiotherapy and immunotherapy. These SRBs include smart fiducial markers …