[HTML][HTML] Cyanobacteria, Cyanotoxins, and Neurodegenerative Diseases: Dangerous Liaisons

P Sini, TBC Dang, M Fais, M Galioto… - International journal of …, 2021 - mdpi.com
The prevalence of neurodegenerative disease (ND) is increasing, partly owing to extensions
in lifespan, with a larger percentage of members living to an older age, but the ND aetiology …

Considerations for amino acid analysis by liquid chromatography-tandem mass spectrometry: A tutorial review

JP Violi, DP Bishop, MP Padula, JR Steele… - TrAC Trends in …, 2020 - Elsevier
Amino acids are present in a variety of matrices from biological fluids to plant and animal
tissues. We discuss options for amino acid extraction, sample clean-up and protein …

Microbial BMAA and the pathway for Parkinson's disease neurodegeneration

D Nunes-Costa, JD Magalhães… - Frontiers in aging …, 2020 - frontiersin.org
The neurotoxin β-N-methylamino-L-alanine (BMAA) is a natural non-proteinogenic diamino
acid produced by several species of both prokaryotic (cyanobacteria) and eukaryotic …

Glyphosate's synergistic toxicity in combination with other factors as a cause of chronic kidney disease of unknown origin

S Gunatilake, S Seneff, L Orlando - International journal of environmental …, 2019 - mdpi.com
Chronic kidney disease of unknown etiology (CKDu) is a global epidemic. Sri Lanka has
experienced a doubling of the disease every 4 or 5 years since it was first identified in the …

Microbial BMAA elicits mitochondrial dysfunction, innate immunity activation, and Alzheimer's disease features in cortical neurons

DF Silva, E Candeias, AR Esteves… - Journal of …, 2020 - Springer
Background After decades of research recognizing it as a complex multifactorial disorder,
sporadic Alzheimer's disease (sAD) still has no known etiology. Adding to the myriad of …

[HTML][HTML] Detection of β-N-methylamino-l-alanine in postmortem olfactory bulbs of Alzheimer's disease patients using UHPLC-MS/MS: An autopsy case-series study

SP Garamszegi, SA Banack, LL Duque, JS Metcalf… - Toxicology Reports, 2023 - Elsevier
Introduction Cyanobacterial blooms produce toxins that may become aerosolized,
increasing health risks through inhalation exposures. Health related effects on the lower …

Detection of the suspected neurotoxin β-methylamino-l-alanine (BMAA) in cyanobacterial blooms from multiple water bodies in Eastern Australia

BJ Main, LC Bowling, MP Padula, DP Bishop… - Harmful Algae, 2018 - Elsevier
The emerging toxin β-methylamino-l-alanine (BMAA) has been linked to the development of
a number of neurodegenerative diseases in humans including amyotrophic lateral sclerosis …

Cyanobacterial neurotoxins: Their occurrence and mechanisms of toxicity

KJ Rodgers, BJ Main, K Samardzic - Neurotoxicity Research, 2018 - Springer
Cyanobacteria are some of the oldest organisms on earth, and have evolved to produce a
battery of toxic metabolites, including hepatotoxins, dermatoxins, and neurotoxins. In this …

Metabolic profiling of zebrafish (Danio rerio) embryos by NMR spectroscopy reveals multifaceted toxicity of β-methylamino-L-alanine (BMAA)

U Roy, L Conklin, J Schiller, J Matysik, JP Berry… - Scientific reports, 2017 - nature.com
Abstract β-methylamino-L-alanine (BMAA) has been linked to several interrelated
neurodegenerative diseases. Despite considerable research, specific contributions of BMAA …

Environmental bacteria as triggers to brain disease: Possible mechanisms of toxicity and associated human risk

A Courtier, D Potheret, P Giannoni - Life Sciences, 2022 - Elsevier
Aims Brain disease, in its many forms, has recently demonstrated a great socio-economic
impact and represents one of the hardest challenges of present research. Although each …