Amyotrophic lateral sclerosis (ALS) is a fatal disease, characterized by the degeneration of
both upper and lower motor neurons. Despite decades of research, we still to date lack a …

Motor circuits represent the main output of the central nervous system and produce dynamic
behaviors ranging from relatively simple rhythmic activities like swimming in fish and …

Transplanting human neural progenitor cells is a promising method of replenishing the lost
neurons after spinal cord injury (SCI), but differentiating neural progenitor cells into the …

To understand how the spinal cord enacts complex sensorimotor functions, researchers
have studied, classified, and functionally probed it's many neuronal populations for over a …

In this review, we discuss motor circuit assembly starting from neuronal stem cells. Until
recently, studies of neuronal stem cells focused on how a relatively small pool of stem cells …

Control of musculoskeletal systems depends on integration of voluntary commands and
somatosensory feedback in the complex neural circuits of the spinal cord. It has been …

The central pattern generator (CPG) is a key neural-circuit component of the locomotion
control system. Recently, numerous molecular and genetic approaches have been …

We describe and analyze a computational model of neural circuits in the mammalian spinal
cord responsible for generating and shaping locomotor-like oscillations. The model …

The basic rhythmic activity characteristic of locomotion in mammals is generated by a neural
network, located in the spinal cord, known as the locomotor central pattern generator (CPG) …

In this review, we are considering an actively developing tool in neuroscience—robotic
modeling. The new perspective and existing application fields, tools, and methods are …