Rheumatoid arthritis (RA) is characterized by inflammation and destruction of bone and
cartilage in affected joints. Autoimmune responses lead to increased osteoclastic bone …

Rheumatoid arthritis (RA) is an autoimmune disease that involves multiple joints bilaterally.
It is characterized by an inflammation of the tendon (tenosynovitis) resulting in both cartilage …

Rheumatoid arthritis (RA) is an incurable systemic autoimmune disease. Disease
progression leads to joint deformity and associated loss of function, which significantly …

The biology of bone healing is a rapidly developing science. Advances in transgenic and
gene‐targeted mice have enabled tissue and cell‐specific investigations of skeletal …

The immune and skeletal systems share a variety of molecules, including cytokines,
chemokines, hormones, receptors, and transcription factors. Bone cells interact with immune …

Periodontal disease is an inflammatory disease caused by periodontopathogenic bacteria,
which eventually leads to bone tissue (alveolar bone) destruction as inflammation persists …

Bone erosion is a central feature of rheumatoid arthritis and is associated with disease
severity and poor functional outcome. Erosion of periarticular cortical bone, the typical …

Bone remodeling in the adult skeleton facilitates the removal and replacement of damaged
and old bone to maintain bone quality. Tight coordination of bone resorption and bone …

Although the introduction of tumor necrosis factor (TNF) inhibitors represented a significant
advance in the treatment of rheumatoid arthritis (RA), traditional anti-TNFα antibodies are …

Rheumatoid arthritis is the most common inflammatory arthritis and is a major cause of
disability. It existed in early Native American populations several thousand years ago but …