Studies on preparation and evaluation of soluble 1: 1 stoichiometric curcumin complex for colorectal cancer treatment

JMM Mohamed, F Ahmad, A Alqahtani, VK Raju… - Trends in …, 2021 - tis.wu.ac.th
This study investigates the complex of curcumin (CMN), which has enhanced solubility and
hence, higher cytotoxicity compared to free CMN. Insilco molecular modelling and phase …

Superfast Synthesis of Stabilized Silver Nanoparticles Using Aqueous Allium sativum (Garlic) Extract and Isoniazid Hydrazide Conjugates: Molecular Docking and In …

JMM Mohamed, A Alqahtani, TVA Kumar, AA Fatease… - Molecules, 2021 - mdpi.com
Green synthesis of silver nanoparticles (AgNPs) was synthesized from fresh garlic extract
coupled with isoniazid hydrazide (INH), a commonly used antibiotic to treat tuberculosis. A …

The unique carboxymethyl fenugreek gum gel loaded itraconazole self-emulsifying nanovesicles for topical onychomycosis treatment

A Alqahtani, B Raut, S Khan, JMM Mohamed… - Polymers, 2022 - mdpi.com
The novel itraconazole (ITZ) nail penetration enhancing self-emulsifying nanovesicles (ITZ-
nPEVs) loaded in carboxymethyl fenugreek gum (CMFG) gel circumvent the systemic …

Human hair keratin composite scaffold: characterisation and biocompatibility study on NIH 3T3 fibroblast cells

JMM Mohamed, A Alqahtani, A Al Fatease, T Alqahtani… - Pharmaceuticals, 2021 - mdpi.com
The aim of this study was to transform human hair keratin waste into a scaffold for soft tissue
engineering to heal wounds. The keratin was extracted using the Shindai method. Keratin …

[HTML][HTML] Polymeric ethosomal gel loaded with nimodipine: Optimisation, pharmacokinetic and histopathological analysis

JMM Mohamed, BA Khan, V Rajendran… - Saudi pharmaceutical …, 2022 - Elsevier
This study was performed with the main objective of formulating and evaluating the potential
of ethosomesl gel (Etho gel) to deliver nimodipine (NiM) for cardiovascular disease, a potent …

[HTML][HTML] Preparation of carrageenan/chitosan-based (N, N, N-trimeth (yl chitosan chloride) silver nanocomposites as pH sensitive carrier for effective controlled …

MW El-Maadawy, RR Mohamed, DH Hanna - OpenNano, 2022 - Elsevier
Purpose This work aims to formulate a novel pH-sensitive biocompatible metallic
nanocomposite as a carrier for hydrophobic drugs with efficient loading and controlled drug …

Preparation of soluble complex of curcumin for the potential antagonistic effects on human colorectal adenocarcinoma cells

JMM Mohamed, A Alqahtani, BA Khan, A Al Fatease… - Pharmaceuticals, 2021 - mdpi.com
This study was designed to investigate the effects of curcumin (CMN) soluble complex (SC)
prepared by melt casting (HM) and hot-melt extrusion (HME) technology. Phase solubility …

[Retracted] Ameliorated Stomach Specific Floating Microspheres for Emerging Health Pathologies Using Polymeric Konjac Glucomannan‐Based Domperidone

JMM Mohamed, N Mahajan… - BioMed Research …, 2022 - Wiley Online Library
The goal of this study was to use polymeric konjac glucomannan (KGM), Kollidon VA 64
(KVA64), and glutaraldehyde to ameliorate stomach specific floating microspheres (SSFM) …

[Retracted] 5‐Fluorouracil‐Loaded PLGA Nanoparticles: Formulation, Physicochemical Characterisation, and In VitroAnti‐Cancer Activity

RM Gahtani, A Alqahtani, T Alqahtani… - Bioinorganic …, 2023 - Wiley Online Library
The major goal of this investigation was to prepare a drug delivery of polymeric
nanoparticles (NPs) from 5‐fluorouracil (FU) that could be delivered intravenously and …

Targeted drug administration onto cancer cells using hyaluronic acid–quercetin-conjugated silver nanoparticles

RH Al-Serwi, MA Eladl, M El-Sherbiny, MA Saleh… - Molecules, 2023 - mdpi.com
Quercetin (QtN) displays low systemic bioavailability caused by poor water solubility and
instability. Consequently, it exerts limited anticancer action in vivo. One solution to increase …