A brief review of in vitro models for injury and regeneration in the peripheral nervous system
P Varier, G Raju, P Madhusudanan, C Jerard… - International Journal of …, 2022 - mdpi.com
Nerve axonal injury and associated cellular mechanisms leading to peripheral nerve
damage are important topics of research necessary for reducing disability and enhancing …
damage are important topics of research necessary for reducing disability and enhancing …
Membrane mechanics dictate axonal pearls-on-a-string morphology and function
JM Griswold, M Bonilla-Quintana, R Pepper… - Nature …, 2024 - nature.com
Axons are ultrathin membrane cables that are specialized for the conduction of action
potentials. Although their diameter is variable along their length, how their morphology is …
potentials. Although their diameter is variable along their length, how their morphology is …
Microtubule dynamics following central and peripheral nervous system axotomy
R Kulkarni, A Thakur, H Kumar - ACS Chemical Neuroscience, 2022 - ACS Publications
Disturbance in the neuronal network leads to instability in the microtubule (MT) railroad of
axons, causing hindrance in the intra-axonal transport and making it difficult to re-establish …
axons, causing hindrance in the intra-axonal transport and making it difficult to re-establish …
Onsager's variational principle in active soft matter
Onsagers variational principle (OVP) was originally proposed by Lars Onsager in 1931 [L.
Onsager, Phys. Rev., 1931, 37, 405]. This fundamental principle provides a very powerful …
Onsager, Phys. Rev., 1931, 37, 405]. This fundamental principle provides a very powerful …
Application of Force to a Syndecan-4 Containing Complex With Thy-1–αVβ3 Integrin Accelerates Neurite Retraction
F Burgos-Bravo, S Martínez-Meza… - Frontiers in molecular …, 2020 - frontiersin.org
Inflammation contributes to the genesis and progression of chronic diseases, such as cancer
and neurodegeneration. Upregulation of integrins in astrocytes during inflammation induces …
and neurodegeneration. Upregulation of integrins in astrocytes during inflammation induces …
“Looping in” mechanics: Mechanobiologic regulation of the nucleus and the epigenome
Cells respond to physical cues in their microenvironment. These cues result in changes in
cell behavior, some of which are transient, and others of which are permanent …
cell behavior, some of which are transient, and others of which are permanent …
Mechanisms of local stress amplification in axons near the gray-white matter interface
Diffuse axonal injury is a primary neuropathological feature of concussion and is thought to
greatly contribute to the classical symptoms of decreased processing speed and memory …
greatly contribute to the classical symptoms of decreased processing speed and memory …
Generation of contractile forces by three-dimensional bundled axonal tracts in micro-tissue engineered neural networks
D Chouhan, WJ Gordián Vélez, LA Struzyna… - Frontiers in Molecular …, 2024 - frontiersin.org
Axonal extension and retraction are ongoing processes that occur throughout all
developmental stages of an organism. The ability of axons to produce mechanical forces …
developmental stages of an organism. The ability of axons to produce mechanical forces …
The Axonal Actin Filament Cytoskeleton: Structure, Function, and Relevance to Injury and Degeneration
G Gallo - Molecular Neurobiology, 2024 - Springer
Early investigations of the neuronal actin filament cytoskeleton gave rise to the notion that,
although growth cones exhibit high levels of actin filaments, the axon shaft exhibits low …
although growth cones exhibit high levels of actin filaments, the axon shaft exhibits low …
Fundamental characteristics of neuron adhesion revealed by forced peeling and time-dependent healing
A current bottleneck in the advance of neurophysics is the lack of reliable methods to
quantitatively measure the interactions between neural cells and their microenvironment …
quantitatively measure the interactions between neural cells and their microenvironment …