Halimane diterpenoids: sources, structures, nomenclature and biological activities

AM Roncero, IE Tobal, RF Moro, D Díez… - Natural product …, 2018 - pubs.rsc.org
Covering: 1970 to 2017 Diterpenes with a halimane skeleton constitute a small group of
natural products that can be biogenetically considered as being between labdane and …

Diterpenoids

JR Hanson - Natural Product Reports, 2003 - pubs.rsc.org
Covering 2001. Previous review: Nat. Prod. Rep., 2002, 19, 125. The review covers the
isolation and structures of diterpenoids including labdanes, clerodanes, pimaranes …

Halimanes and cancer: ent-halimic acid as a starting material for the synthesis of antitumor drugs

AM Roncero, IE Tobal, RF Moro, D Diez… - Frontiers in …, 2023 - frontiersin.org
The development of new anti-cancer agents is an urgent necessity nowadays, as it is one of
the major causes of mortality worldwide. Many drugs currently used are derived from natural …

7-6-5 Tricarbocyclic diterpenes: Valparanes, mulinanes, cyathanes, homoverrucosanes, and related ones

IS Marcos, RF Moro, A Gil-Mesón, D Díez - Studies in natural products …, 2016 - Elsevier
Valparanes, mulinanes, cyathanes, and homoverrucosanes are diterpenes that are broadly
distributed in nature and have a 7-6-5 tricarbocyclic system. In contrast with other families or …

Total synthesis of natural fregenedadiol and its diacetate, rearranged labdanes with aromatized B ring

SC Philkhana, DS Reddy - Tetrahedron Letters, 2017 - Elsevier
Labdane based natural products are most abundant and widely distributed in nature with
many compounds exhibiting exceptional biological properties. Fregenedadiol is a bicyclic …

Covilanone: a new rearranged labdane type diterpene

JML Rodilla, MI Ismael, LA Silva, JPC Serrano… - Tetrahedron letters, 2002 - Elsevier
A bicyclic diterpene triol with a new rearranged labdane carbon skeleton was isolated from
the aerial parts of Halimium viscosum (Willk.) Pinto da Silva (S. João da Pesqueira). Its …

Diterpene Acids as Starting Materials for the Synthesis of Biologically Active Compounds

IE Tobal, AM Roncero, RF Moro… - Chiral Building Blocks …, 2022 - Wiley Online Library
The synthesis of enantiomerically pure molecules constitutes a milestone in organic
synthesis. As the biological environment is asymmetric, the biologically active compounds …

ent-Hydrohalimic acid transformations: synthesis of a diterpenic bislactone

JML Rodilla, MLA Silva, D Dı́ez, JG Urones… - Tetrahedron …, 2004 - Elsevier
ent-Hydrohalimic acid transformations: synthesis of a diterpenic bislactone - ScienceDirect
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The Methylene-Cycloalkylacetate (MCA) Scaffold in Terpenyl Compounds with Potential Pharmacological Activities

IE Tobal, AM Roncero, RF Moro, D Díez, IS Marcos - Molecules, 2019 - mdpi.com
Recently, the methylene-cycloakylacetate (MCA) scaffold has been reported as a potential
pharmacophore for neurite outgrowth activity. In this work, natural diterpenes that embed …